Anti-S1PR5 Antibody (CAB20164)
- SKU:
- CAB20164
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- EDG8
- Synonyms:
- S1P5
- Synonyms:
- Edg-8
- Synonyms:
- SPPR-1
- Synonyms:
- SPPR-2
Description
| Product Name: | S1PR5 Rabbit pAb |
| Product Code: | CAB20164 |
| Size: | 50uL, 100uL |
| Synonyms: | EDG8, S1P5, Edg-8, SPPR-1, SPPR-2 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human S1PR5. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:1000 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | MCF7, Jurkat |
| Immunogen: | Recombinant protein of human S1PR5. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 53637 |
| Uniprot: | Q9H228 |
| Calculated MW: | 42kDa |
| Observed MW: | 50KDa |
| UniProt Protein Function: | EDG8: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: integral to membrane; plasma membrane Biological Process: regulation of neuron differentiation |
| NCBI Summary: | The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9H228 |
| NCBI GenInfo Identifier: | 62510663 |
| NCBI Gene ID: | 53637 |
| NCBI Accession: | Q9H228.1 |
| UniProt Secondary Accession: | Q9H228,Q6NW11, |
| UniProt Related Accession: | Q9H228 |
| Molecular Weight: | 398 |
| NCBI Full Name: | Sphingosine 1-phosphate receptor 5 |
| NCBI Synonym Full Names: | sphingosine-1-phosphate receptor 5 |
| NCBI Official Symbol: | S1PR5 |
| NCBI Official Synonym Symbols: | EDG8; S1P5; Edg-8; SPPR-1; SPPR-2 |
| NCBI Protein Information: | sphingosine 1-phosphate receptor 5; S1P receptor 5; S1P receptor Edg-8; sphingosine 1-phosphate receptor EDG8; sphingosine 1-phosphate receptor Edg-8; endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-pr |
| UniProt Protein Name: | Sphingosine 1-phosphate receptor 5 |
| UniProt Synonym Protein Names: | Endothelial differentiation G-protein-coupled receptor 8; Sphingosine 1-phosphate receptor Edg-8; S1P receptor Edg-8 |
| UniProt Gene Name: | S1PR5 |
| UniProt Entry Name: | S1PR5_HUMAN |
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