Cell Biology Antibodies 14

Anti-S1PR2 Antibody (CAB18205)

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SKU:
CAB18205
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-S1PR2 Antibody
Antibody SKU:CAB18205
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human S1PR2 .
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:U-87MG, HeLa, Mouse lung, Mouse brain, Mouse spleen
Immunogen:Recombinant protein of human S1PR2 .
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:9294
Uniprot:O95136
Cellular Location:
Calculated MW:39kDa
Observed MW:38kDa
Anti-S1PR2 Antibody (CAB18205)Western blot - S1PR2 Polyclonal Antibody (CAB18205)
Synonyms:EDG5, H218, LPB2, S1P2, AGR16, EDG-5, DFNB68, Gpcr13, S1PR2
Background:This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness.
UniProt Protein Function:EDG5: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Lipid-binding

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function:G-protein coupled receptor activity; G-protein-coupled receptor binding; integrin binding; lipid binding; protein binding

Biological Process: actin cytoskeleton reorganization; activation of MAPK activity; filopodium formation; G-protein coupled receptor protein signaling pathway; positive regulation of cell proliferation

NCBI Summary:This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016]
UniProt Code:O95136
NCBI GenInfo Identifier:38257367
NCBI Gene ID:9294
NCBI Accession:O95136.2
UniProt Secondary Accession:O95136,Q86UN8,
UniProt Related Accession:O95136
Molecular Weight:38,867 Da
NCBI Full Name:Sphingosine 1-phosphate receptor 2
NCBI Synonym Full Names:sphingosine-1-phosphate receptor 2
NCBI Official Symbol:S1PR2  
NCBI Official Synonym Symbols:EDG5; H218; LPB2; S1P2; AGR16; EDG-5; DFNB68; Gpcr13  
NCBI Protein Information:sphingosine 1-phosphate receptor 2
UniProt Protein Name:Sphingosine 1-phosphate receptor 2
UniProt Synonym Protein Names:Endothelial differentiation G-protein coupled receptor 5; Sphingosine 1-phosphate receptor Edg-5; S1P receptor Edg-5
Protein Family:Sphingosine 1-phosphate receptor
UniProt Gene Name:S1PR2  
UniProt Entry Name:S1PR2_HUMAN
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