Antibody Name:	Anti-S100A7 Antibody
Antibody SKU:	CAB1940
Antibody Size:	20uL, 50uL, 100uL
Application:	IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A7 (NP_002954.2).

Application:	IHC
Recommended Dilution:	IHC 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A7 (NP_002954.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MSNT QAER SIIG MIDM FHKY TRRD DKIE KPSL LTMM KENF PNFL SACD KKGT NYLA DVFE KKDK NEDK KIDF SEFL SLLG DIAT DYHK QSHG AAPC SGGS Q
Gene ID:	6278
Uniprot:	P31151
Cellular Location:	Cytoplasm, Secreted
Calculated MW:	11kDa
Observed MW:

Synonyms:

S100A7, PSOR1, S100A7c

Background:

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.

UniProt Protein Function:	S100A7: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq, Jul 2008]
UniProt Protein Details:	Chromosomal Location of Human Ortholog: 1q21 Cellular Component: focal adhesion; endoplasmic reticulum; cytoplasm; extracellular region; nucleus; cytosol Molecular Function:RAGE receptor binding; protein binding; zinc ion binding; calcium ion binding Biological Process: keratinocyte differentiation; sequestering of metal ion; response to reactive oxygen species; epidermis development; innate immune response; response to lipopolysaccharide; angiogenesis; defense response to Gram-negative bacterium
NCBI Summary:	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]
UniProt Code:	P31151
NCBI GenInfo Identifier:	172046820
NCBI Gene ID:	6278
NCBI Accession:	P31151.4
UniProt Secondary Accession:	P31151,Q5SY67, Q6FGE3, Q9H1E2,
UniProt Related Accession:	P31151
Molecular Weight:	101
NCBI Full Name:	Protein S100-A7
NCBI Synonym Full Names:	S100 calcium binding protein A7
NCBI Official Symbol:	S100A7
NCBI Official Synonym Symbols:	PSOR1; S100A7c
NCBI Protein Information:	protein S100-A7; psoriasin 1; S100 calcium-binding protein A7 (psoriasin 1)
UniProt Protein Name:	Protein S100-A7
UniProt Synonym Protein Names:	Psoriasin; S100 calcium-binding protein A7
Protein Family:	Protein
UniProt Gene Name:	S100A7
UniProt Entry Name:	S10A7_HUMAN

	Immunohistochemistry of paraffin-embedded rat lung using S100A7 antibody (CAB1940) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded human esophagus using S100A7 antibody (CAB1940) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded mouse lung using S100A7 antibody (CAB1940) at dilution of 1:100 (40x lens).