Cell Biology Antibodies 7

Anti-S100A7 Antibody (CAB1940)

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SKU:
CAB1940
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-S100A7 Antibody
Antibody SKU:CAB1940
Antibody Size:20uL, 50uL, 100uL
Application:IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A7 (NP_002954.2).
Application:IHC
Recommended Dilution:IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A7 (NP_002954.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSNT QAER SIIG MIDM FHKY TRRD DKIE KPSL LTMM KENF PNFL SACD KKGT NYLA DVFE KKDK NEDK KIDF SEFL SLLG DIAT DYHK QSHG AAPC SGGS Q
Gene ID:6278
Uniprot:P31151
Cellular Location:Cytoplasm, Secreted
Calculated MW:11kDa
Observed MW:
Synonyms:S100A7, PSOR1, S100A7c
Background:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.
UniProt Protein Function:S100A7: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: focal adhesion; endoplasmic reticulum; cytoplasm; extracellular region; nucleus; cytosol

Molecular Function:RAGE receptor binding; protein binding; zinc ion binding; calcium ion binding

Biological Process: keratinocyte differentiation; sequestering of metal ion; response to reactive oxygen species; epidermis development; innate immune response; response to lipopolysaccharide; angiogenesis; defense response to Gram-negative bacterium

NCBI Summary:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]
UniProt Code:P31151
NCBI GenInfo Identifier:172046820
NCBI Gene ID:6278
NCBI Accession:P31151.4
UniProt Secondary Accession:P31151,Q5SY67, Q6FGE3, Q9H1E2,
UniProt Related Accession:P31151
Molecular Weight:101
NCBI Full Name:Protein S100-A7
NCBI Synonym Full Names:S100 calcium binding protein A7
NCBI Official Symbol:S100A7  
NCBI Official Synonym Symbols:PSOR1; S100A7c  
NCBI Protein Information:protein S100-A7; psoriasin 1; S100 calcium-binding protein A7 (psoriasin 1)
UniProt Protein Name:Protein S100-A7
UniProt Synonym Protein Names:Psoriasin; S100 calcium-binding protein A7
Protein Family:Protein
UniProt Gene Name:S100A7  
UniProt Entry Name:S10A7_HUMAN
Anti-S100A7 Antibody (CAB1940)Immunohistochemistry of paraffin-embedded rat lung using S100A7 antibody (CAB1940) at dilution of 1:100 (40x lens).
Anti-S100A7 Antibody (CAB1940)Immunohistochemistry of paraffin-embedded human esophagus using S100A7 antibody (CAB1940) at dilution of 1:100 (40x lens).
Anti-S100A7 Antibody (CAB1940)Immunohistochemistry of paraffin-embedded mouse lung using S100A7 antibody (CAB1940) at dilution of 1:100 (40x lens).
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