Cell Biology Antibodies 17
Anti-S100A4 Antibody (CAB19109)
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- SKU:
- CAB19109
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-S100A4 Antibody |
| Antibody SKU: | CAB19109 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human S100A4 |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, A-549, A375, NIH/3T3, Rat heart |
| Immunogen: | A synthesized peptide derived from human S100A4 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6275 |
| Uniprot: | P26447 |
| Cellular Location: | |
| Calculated MW: | 12kDa |
| Observed MW: | 12kDa |
 | Western blot - S100A4 Rabbit mAb (CAB19109) |
| Synonyms: | 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98, S100A4 |
| Background: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | S100A4: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 1q21 Cellular Component: extracellular space; neuron projection; perinuclear region of cytoplasm; nucleus Molecular Function:identical protein binding; protein binding; RAGE receptor binding; calcium ion binding; actin binding; calcium-dependent protein binding Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; epithelial to mesenchymal transition |
| NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P26447 |
| NCBI GenInfo Identifier: | 115601 |
| NCBI Gene ID: | 6275 |
| NCBI Accession: | P26447.1 |
| UniProt Secondary Accession: | P26447,Q6ICP8, A8K7R8, D3DV46, |
| UniProt Related Accession: | P26447 |
| Molecular Weight: | 101 |
| NCBI Full Name: | Protein S100-A4 |
| NCBI Synonym Full Names: | S100 calcium binding protein A4 |
| NCBI Official Symbol: | S100A4 |
| NCBI Official Synonym Symbols: | 42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98 |
| NCBI Protein Information: | protein S100-A4; protein Mts1; fibroblast-specific protein-1; placental calcium-binding protein; malignant transformation suppression 1; leukemia multidrug resistance associated protein; S100 calcium-binding protein A4 (calcium protein, calvasculin, metas |
| UniProt Protein Name: | Protein S100-A4 |
| UniProt Synonym Protein Names: | Calvasculin; Metastasin; Placental calcium-binding protein; Protein Mts1; S100 calcium-binding protein A4 |
| Protein Family: | Tyrosine-protein kinase |
| UniProt Gene Name: | S100A4 |
| UniProt Entry Name: | S10A4_HUMAN |
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