Cell Biology Antibodies 9

Anti-S100A3 Antibody (CAB4102)

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SKU:
CAB4102
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-S100A3 Antibody
Antibody SKU:CAB4102
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A3 (NP_002951.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:SKOV3, HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A3 (NP_002951.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MARP LEQA VAAI VCTF QEYA GRCG DKYK LCQA ELKE LLQK ELAT WTPT EFRE CDYN KFMS VLDT NKDC EVDF VEYV RSLA CLCL YCHE YFKD CPSE PPCS Q
Gene ID:6274
Uniprot:P33764
Cellular Location:Cytoplasm
Calculated MW:11kDa
Observed MW:12kDa
Synonyms:S100A3, S100E
Background:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown.
UniProt Protein Function:S100A3: Binds both calcium and zinc. Probably binds 2 zinc ions per molecule. May be involved in calcium-dependent cuticle cell differentiation and hair shaft formation. Belongs to the S-100 family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; nucleolus

Molecular Function:zinc ion binding; calcium ion binding

NCBI Summary:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008]
UniProt Code:P33764
NCBI GenInfo Identifier:464729
NCBI Gene ID:6274
NCBI Accession:P33764.1
UniProt Secondary Accession:P33764,Q6FGE4, D3DV51,
UniProt Related Accession:P33764
Molecular Weight:101
NCBI Full Name:Protein S100-A3
NCBI Synonym Full Names:S100 calcium binding protein A3
NCBI Official Symbol:S100A3  
NCBI Official Synonym Symbols:S100E  
NCBI Protein Information:protein S100-A3; S100 calcium-binding protein A3
UniProt Protein Name:Protein S100-A3
UniProt Synonym Protein Names:Protein S-100E; S100 calcium-binding protein A3
Protein Family:Protein
UniProt Gene Name:S100A3  
UniProt Entry Name:S10A3_HUMAN
Anti-S100A3 Antibody (CAB4102)Western blot analysis of extracts of various cell lines, using S100A3 antibody (CAB4102) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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