Cell Death Antibodies 1
Anti-RYBP Antibody (CAB14605)
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- SKU:
- CAB14605
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-RYBP Antibody |
| Antibody SKU: | CAB14605 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RYBP (NP_036366.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse brain, Rat brain |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RYBP (NP_036366.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PSVT KKNT NKKT KPKS DILK DPPS EANS IQSA NATT KTSE TNHT SRPR LKNV DRST AQQL AVTV GNVT VIIT DFKE KTRS SSTS SSTV TSSA GSEQ QNQS SSGS ESTD KGSS RSST PKGD MSAV NDES F |
| Gene ID: | 23429 |
| Uniprot: | Q8N488 |
| Cellular Location: | Cytoplasm, Nucleus, nucleoplasm |
| Calculated MW: | 24kDa |
| Observed MW: | 33kDa |
| Synonyms: | RYBP, AAP1, APAP-1, DEDAF, YEAF1 |
| Background: |
| UniProt Protein Function: | RYBP: Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 3p13 Cellular Component: nucleoplasm; PcG protein complex Molecular Function:protein binding Biological Process: multicellular organismal development |
| UniProt Code: | Q8N488 |
| NCBI GenInfo Identifier: | 78102506 |
| NCBI Gene ID: | 23429 |
| NCBI Accession: | Q8N488.2 |
| UniProt Secondary Accession: | Q8N488,Q9P2W5, Q9UMW4, |
| UniProt Related Accession: | Q8N488 |
| Molecular Weight: | 24,822 Da |
| NCBI Full Name: | RING1 and YY1-binding protein |
| NCBI Synonym Full Names: | RING1 and YY1 binding protein |
| NCBI Official Symbol: | RYBP |
| NCBI Official Synonym Symbols: | AAP1; DEDAF; YEAF1; APAP-1 |
| NCBI Protein Information: | RING1 and YY1-binding protein |
| UniProt Protein Name: | RING1 and YY1-binding protein |
| UniProt Synonym Protein Names: | Apoptin-associating protein 1; APAP-1; Death effector domain-associated factor; DED-associated factor; YY1 and E4TF1-associated factor 1 |
| Protein Family: | RING1 and YY1-binding protein |
| UniProt Gene Name: | RYBP |
| UniProt Entry Name: | RYBP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RYBP Rabbit pAb (CAB14605) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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