Cell Biology Antibodies 6
Anti-RXFP4 Antibody (CAB15978)
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- SKU:
- CAB15978
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RXFP4 Antibody |
| Antibody SKU: | CAB15978 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 305-374 of human RXFP4 (NP_871001.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, Mouse brain, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 305-374 of human RXFP4 (NP_871001.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NPVL YCLL RREP RQAL AGTF RDLR LRLW PQGG GWVQ QVAL KQVG RRWV ASNP RESR PSTL LTNL DRGT PG |
| Gene ID: | 339403 |
| Uniprot: | Q8TDU9 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 41kDa |
| Observed MW: | 40kDa |
| Synonyms: | RXFP4, GPCR142, GPR100, RLN3R2, RXFPR4 |
| Background: | GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]). |
| UniProt Protein Function: | High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation. |
| NCBI Summary: | GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8TDU9 |
| NCBI GenInfo Identifier: | 32490567 |
| NCBI Gene ID: | 339403 |
| NCBI Accession: | NP_871001.1 |
| UniProt Secondary Accession: | Q8TDU9,Q3MJB1, Q8NGZ8, B0M0L4, |
| UniProt Related Accession: | Q8TDU9 |
| Molecular Weight: | 41,141 Da |
| NCBI Full Name: | relaxin-3 receptor 2 |
| NCBI Synonym Full Names: | relaxin family peptide/INSL5 receptor 4 |
| NCBI Official Symbol: | RXFP4 |
| NCBI Official Synonym Symbols: | GPR100; RLN3R2; RXFPR4; GPCR142 |
| NCBI Protein Information: | relaxin-3 receptor 2 |
| UniProt Protein Name: | Relaxin-3 receptor 2 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 100; G-protein coupled receptor GPCR142; Insulin-like peptide INSL5 receptor; Relaxin family peptide receptor 4 |
| Protein Family: | Relaxin-3 receptor |
| UniProt Gene Name: | RXFP4 |
 | Western blot analysis of extracts of various cell lines, using RXFP4 antibody (CAB15978) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 1s. |
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