Cell Biology Antibodies 1
Anti-RXFP3 Antibody (CAB10303)
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- SKU:
- CAB10303
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RXFP3 Antibody |
| Antibody SKU: | CAB10303 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human RXFP3 (NP_057652.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, BxPC-3, Mouse brain, Mouse kidney, Rat brain, Rat pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human RXFP3 (NP_057652.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MQMA DAAT IATM NKAA GGDK LAEL FSLV PDLL EAAN TSGN ASLQ LPDL WWEL GLEL PDGA PPGH PPGS GGAE SADT EARV |
| Gene ID: | 51289 |
| Uniprot: | Q9NSD7 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 51kDa |
| Observed MW: | 60kDa |
| Synonyms: | RXFP3, GPCR135, RLN3R1, RXFPR3, SALPR |
| Background: |
| UniProt Protein Function: | RLN3R1: Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1 Chromosomal Location of Human Ortholog: 5p15.1-p14 Cellular Component: cytosol; integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; peptide receptor activity, G-protein coupled Biological Process: elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); neuropeptide signaling pathway; positive regulation of cytokinesis |
| UniProt Code: | Q9NSD7 |
| NCBI GenInfo Identifier: | 20455271 |
| NCBI Gene ID: | 51289 |
| NCBI Accession: | Q9NSD7.1 |
| UniProt Secondary Accession: | Q9NSD7,Q14DA5, |
| UniProt Related Accession: | Q9NSD7 |
| Molecular Weight: | 51,124 Da |
| NCBI Full Name: | Relaxin-3 receptor 1 |
| NCBI Synonym Full Names: | relaxin/insulin like family peptide receptor 3 |
| NCBI Official Symbol: | RXFP3 |
| NCBI Official Synonym Symbols: | SALPR; RLN3R1; RXFPR3; GPCR135 |
| NCBI Protein Information: | relaxin-3 receptor 1 |
| UniProt Protein Name: | Relaxin-3 receptor 1 |
| UniProt Synonym Protein Names: | G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; Relaxin family peptide receptor 3; Somatostatin- and angiotensin-like peptide receptor |
| Protein Family: | Relaxin-3 receptor |
| UniProt Gene Name: | RXFP3 |
| UniProt Entry Name: | RL3R1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RXFP3 antibody (CAB10303) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20s. |
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