Name: Anti-RXFP2 Antibody (CAB14440)
Brand: Cell Biology Antibodies 5
SKU: CAB14440
Availability: OutOfStock

Antibody Name:	Anti-RXFP2 Antibody
Antibody SKU:	CAB14440
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human RXFP2 (NP_570718.1).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	U-87MG, 293T, HeLa, K-562, Mouse brain, Mouse kidney, Mouse testis, Rat brain, Rat kidney

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human RXFP2 (NP_570718.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	CGDT SGWA TIFG TVHG NANS VALT QECF LKQY PQCC DCKE TELE CVNG DLKS VPMI SNNV TLLS LKKN KIHS LPDK VFIK YTKL KKIF LQHN CIRH ISRK A
Gene ID:	122042
Uniprot:	Q8WXD0
Cellular Location:	Cell membrane, Multi-pass membrane protein
Calculated MW:	83kDa/86kDa
Observed MW:	86kDa

Synonyms:	RXFP2, GPR106, GREAT, INSL3R, LGR8, LGR8.1, RXFPR2
Background:	This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt Protein Function:	LGR8: the relaxin receptor is a G-protein coupled receptor (GPCR) that leads to the stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).
UniProt Protein Details:	Protein type:Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1 Chromosomal Location of Human Ortholog: 13q13.1 Cellular Component: plasma membrane Molecular Function:G-protein coupled receptor activity Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger Disease: Cryptorchidism, Unilateral Or Bilateral
NCBI Summary:	This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
UniProt Code:	Q8WXD0
NCBI GenInfo Identifier:	21362625
NCBI Gene ID:	122042
NCBI Accession:	Q8WXD0.1
UniProt Secondary Accession:	Q8WXD0,Q3KU23, B1ALE9,
UniProt Related Accession:	Q8WXD0
Molecular Weight:	83,736 Da
NCBI Full Name:	Relaxin receptor 2
NCBI Synonym Full Names:	relaxin/insulin like family peptide receptor 2
NCBI Official Symbol:	RXFP2
NCBI Official Synonym Symbols:	LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2
NCBI Protein Information:	relaxin receptor 2
UniProt Protein Name:	Relaxin receptor 2
UniProt Synonym Protein Names:	G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2
Protein Family:	Relaxin receptor
UniProt Gene Name:	RXFP2
UniProt Entry Name:	RXFP2_HUMAN

Western blot analysis of extracts of various cell lines, using RXFP2 antibody (CAB14440) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.

Antibodies

Anti-RXFP2 Antibody (CAB14301)

RXFP2 Antibody (PACO02454)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)