Cell Biology Antibodies 1
Anti-RTN4RL1 Antibody (CAB10021)
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- SKU:
- CAB10021
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RTN4RL1 Antibody |
| Antibody SKU: | CAB10021 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human RTN4RL1 (NP_848663.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:4000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human RTN4RL1 (NP_848663.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LRRL TTLF LFNN SLSE LQGE CLAP LGAL EFLR LNGN PWDC GCRA RSLW EWLQ RFRG SSSA VPCV SPGL RHGQ DLKL LRAE DFRN CTGP ASPH QIKS HTLT TTDR AARK EHHS PHGP TRSK GHPH GPRP GHRK PGKN CTNP RNRN QISK AGAG KQAP ELPD YAPD YQHK FSFD IMPT ARPK RKGK CARR TPIR APSG VQQA S |
| Gene ID: | 146760 |
| Uniprot: | Q86UN2 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor |
| Calculated MW: | 49kDa |
| Observed MW: | 49kDa |
| Synonyms: | RTN4RL1, NGRH2, NgR3 |
| Background: |
| UniProt Protein Function: | RTN4RL1: May play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Belongs to the Nogo receptor family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 17p13.3 Cellular Component: anchored to plasma membrane; cell surface; cytoplasm Molecular Function:protein binding; protein kinase inhibitor activity; receptor activity Biological Process: axon regeneration; cytokine and chemokine mediated signaling pathway; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity |
| UniProt Code: | Q86UN2 |
| NCBI GenInfo Identifier: | 74714017 |
| NCBI Gene ID: | 146760 |
| NCBI Accession: | Q86UN2.1 |
| UniProt Secondary Accession: | Q86UN2,Q8ND46, A1A5E3, |
| UniProt Related Accession: | Q86UN2 |
| Molecular Weight: | 49,065 Da |
| NCBI Full Name: | Reticulon-4 receptor-like 1 |
| NCBI Synonym Full Names: | reticulon 4 receptor like 1 |
| NCBI Official Symbol: | RTN4RL1 |
| NCBI Official Synonym Symbols: | NgR3; NGRH2 |
| NCBI Protein Information: | reticulon-4 receptor-like 1 |
| UniProt Protein Name: | Reticulon-4 receptor-like 1 |
| UniProt Synonym Protein Names: | Nogo receptor-like 2; Nogo-66 receptor homolog 2; Nogo-66 receptor-related protein 3; NgR3 |
| UniProt Gene Name: | RTN4RL1 |
| UniProt Entry Name: | R4RL1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RTN4RL1 antibody (CAB10021) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20s. |
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