Cell Biology Antibodies 1

Anti-RTN4RL1 Antibody (CAB10021)

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SKU:
CAB10021
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-RTN4RL1 Antibody
Antibody SKU:CAB10021
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human RTN4RL1 (NP_848663.1).
Application:WB
Recommended Dilution:WB 1:1000 - 1:4000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human RTN4RL1 (NP_848663.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LRRL TTLF LFNN SLSE LQGE CLAP LGAL EFLR LNGN PWDC GCRA RSLW EWLQ RFRG SSSA VPCV SPGL RHGQ DLKL LRAE DFRN CTGP ASPH QIKS HTLT TTDR AARK EHHS PHGP TRSK GHPH GPRP GHRK PGKN CTNP RNRN QISK AGAG KQAP ELPD YAPD YQHK FSFD IMPT ARPK RKGK CARR TPIR APSG VQQA S
Gene ID:146760
Uniprot:Q86UN2
Cellular Location:Cell membrane, GPI-anchor, Lipid-anchor
Calculated MW:49kDa
Observed MW:49kDa
Synonyms:RTN4RL1, NGRH2, NgR3
Background:
UniProt Protein Function:RTN4RL1: May play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Belongs to the Nogo receptor family.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: anchored to plasma membrane; cell surface; cytoplasm

Molecular Function:protein binding; protein kinase inhibitor activity; receptor activity

Biological Process: axon regeneration; cytokine and chemokine mediated signaling pathway; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity

UniProt Code:Q86UN2
NCBI GenInfo Identifier:74714017
NCBI Gene ID:146760
NCBI Accession:Q86UN2.1
UniProt Secondary Accession:Q86UN2,Q8ND46, A1A5E3,
UniProt Related Accession:Q86UN2
Molecular Weight:49,065 Da
NCBI Full Name:Reticulon-4 receptor-like 1
NCBI Synonym Full Names:reticulon 4 receptor like 1
NCBI Official Symbol:RTN4RL1  
NCBI Official Synonym Symbols:NgR3; NGRH2  
NCBI Protein Information:reticulon-4 receptor-like 1
UniProt Protein Name:Reticulon-4 receptor-like 1
UniProt Synonym Protein Names:Nogo receptor-like 2; Nogo-66 receptor homolog 2; Nogo-66 receptor-related protein 3; NgR3
UniProt Gene Name:RTN4RL1  
UniProt Entry Name:R4RL1_HUMAN
Anti-RTN4RL1 Antibody (CAB10021)Western blot analysis of extracts of various cell lines, using RTN4RL1 antibody (CAB10021) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20s.
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