Cell Biology Antibodies 15
Anti-RTN4R Antibody (CAB5847)
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- SKU:
- CAB5847
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RTN4R Antibody |
| Antibody SKU: | CAB5847 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 244-473 of human RTN4R (NP_075380.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, BT-474, U-937, Mouse brain, Mouse heart, Mouse skeletal muscle, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 244-473 of human RTN4R (NP_075380.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EALA PLRA LQYL RLND NPWV CDCR ARPL WAWL QKFR GSSS EVPC SLPQ RLAG RDLK RLAA NDLQ GCAV ATGP YHPI WTGR ATDE EPLG LPKC CQPD AADK ASVL EPGR PASA GNAL KGRV PPGD SPPG NGSG PRHI NDSP FGTL PGSA EPPL TAVR PEGS EPPG FPTS GPRR RPGC SRKN RTRS HCRL GQAG SGGG GTGD SEGS GALP SLTC SLTP LGLA LVLW TVLG PC |
| Gene ID: | 65078 |
| Uniprot: | Q9BZR6 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor |
| Calculated MW: | 50kDa |
| Observed MW: | 44-100kDa |
| Synonyms: | RTN4R, NGR, NOGOR |
| Background: | This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. |
| UniProt Protein Function: | RTN4R: Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development. Belongs to the Nogo receptor family. |
| UniProt Protein Details: | Protein type:Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 22q11.21 Cellular Component: cell surface; growth cone; endoplasmic reticulum; plasma membrane Molecular Function:protein binding; receptor activity Biological Process: nerve growth factor receptor signaling pathway; axonogenesis; negative regulation of axonogenesis; regulation of axonogenesis Disease: Schizophrenia |
| NCBI Summary: | This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BZR6 |
| NCBI GenInfo Identifier: | 25453267 |
| NCBI Gene ID: | 65078 |
| NCBI Accession: | Q9BZR6.1 |
| UniProt Related Accession: | Q9BZR6 |
| Molecular Weight: | |
| NCBI Full Name: | Reticulon-4 receptor |
| NCBI Synonym Full Names: | reticulon 4 receptor |
| NCBI Official Symbol: | RTN4R |
| NCBI Official Synonym Symbols: | NGR; NOGOR |
| NCBI Protein Information: | reticulon-4 receptor |
| UniProt Protein Name: | Reticulon-4 receptor |
| UniProt Synonym Protein Names: | Nogo receptor; NgR; Nogo-66 receptor |
| Protein Family: | Reticulon-4 receptor |
| UniProt Gene Name: | RTN4R |
| UniProt Entry Name: | RTN4R_HUMAN |
 | Western blot - RTN4R Polyclonal Antibody (CAB5847) |
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