Cell Biology Antibodies 2

Anti-RSU1 Antibody (CAB11592)

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SKU:
CAB11592
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-RSU1 Antibody
Antibody SKU:CAB11592
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human RSU1 (NP_036557.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:A-431, U-87MG, B cells, SKOV3, Mouse heart, Mouse lung, Mouse kidney, Rat heart, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human RSU1 (NP_036557.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSKS LKKL VEES REKN QPEV DMSD RGIS NMLD VNGL FTLS HITQ LVLS HNKL TMVP PNIA ELKN LEVL NFFN NQIE ELPT QISS LQKL KHLN LGMN RLNT LPRG FGSL PALE VLDL TYNN LSEN SLPG NFFY LTTL RALY LSDN DFEI LPPD IGKL TKLQ ILSL RDND LISL PKEI GELT QLKE LHIQ GNRL TVLP PELG NLDL TGQK QVFK AENN PWVT PIAD QFQL GVSH VFEY IRSE TYKY LYGR HMQA NPEP PKKN NDKS KKIS RKPL AAKN R
Gene ID:6251
Uniprot:Q15404
Cellular Location:
Calculated MW:25kDa/31kDa
Observed MW:31kDa
Synonyms:RSU1, RSP-1
Background:This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors.
UniProt Protein Function:RSU1: a leucine-rich protein that interacts with the IPP (integrin-linked kinase (ILK)/PINCH1/ parvin) focal adhesion complex. Plays a role in Ras signaling pathways. Capable of suppressing v-Ras transformation in vitro
UniProt Protein Details:

Protein type:Cell adhesion

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: focal adhesion; cytosol

Molecular Function:protein binding

Biological Process: Ras protein signal transduction; signal transduction; positive regulation of GTPase activity

NCBI Summary:This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008]
UniProt Code:Q15404
NCBI GenInfo Identifier:2498866
NCBI Gene ID:6251
NCBI Accession:Q15404.3
UniProt Related Accession:Q15404
Molecular Weight:32 kDa
NCBI Full Name:Ras suppressor protein 1
NCBI Synonym Full Names:Ras suppressor protein 1
NCBI Official Symbol:RSU1  
NCBI Official Synonym Symbols:RSP-1  
NCBI Protein Information:ras suppressor protein 1
UniProt Protein Name:Ras suppressor protein 1
Protein Family:Ras suppressor protein
UniProt Gene Name:RSU1  
UniProt Entry Name:RSU1_HUMAN
Anti-RSU1 Antibody (CAB11592)Western blot analysis of extracts of various cell lines, using RSU1 antibody (CAB11592) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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