Epigenetics & Nuclear Signaling Antibodies 4
Anti-RSRC1 Antibody (CAB7210)
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- SKU:
- CAB7210
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-RSRC1 Antibody |
| Antibody SKU: | CAB7210 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 117-276 of human RSRC1 (NP_001258763.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SW480, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 117-276 of human RSRC1 (NP_001258763.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EHLP PAEQ AKAR LQLV LEAA AKAD EALK AKER NEEE AKRR KEED QATL VEQV KRVK EIEA IESD SFVQ QTFR SSKE VKKS VEPS EVKQ ATST SGPA SAVA DPPS TEKE IDPT SIPT AIKY QDDN SLAH PNLF IEKA DAEE KWFK RLIA LRQE RLMG SPVA |
| Gene ID: | 51319 |
| Uniprot: | Q96IZ7 |
| Cellular Location: | Cytoplasm, Nucleus, Nucleus speckle |
| Calculated MW: | 31kDa/38kDa |
| Observed MW: | 38kDa |
| Synonyms: | RSRC1, BM-011, SFRS21, SRrp53 |
| Background: | This gene encodes a member of the serine and arginine rich-related protein family. The encoded protein is involved in both constitutive and alternative mRNA splicing. This gene may be associated with schizophrenia. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | RSRC1: Plays a role in pre-mRNA splicing. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA splicing Chromosomal Location of Human Ortholog: 3q25.32 Cellular Component: cytoplasm; nuclear speck; nucleus Molecular Function:protein binding Biological Process: nuclear mRNA splicing, via spliceosome; alternative nuclear mRNA splicing, via spliceosome; response to antibiotic; RNA splicing; nucleocytoplasmic transport; protein amino acid phosphorylation |
| NCBI Summary: | This gene encodes a member of the serine and arginine rich-related protein family. The encoded protein is involved in both constitutive and alternative mRNA splicing. This gene may be associated with schizophrenia. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] |
| UniProt Code: | Q96IZ7 |
| NCBI GenInfo Identifier: | 61216831 |
| NCBI Gene ID: | 51319 |
| NCBI Accession: | Q96IZ7.1 |
| UniProt Secondary Accession: | Q96IZ7,Q96QK2, Q9NZE5, A8K2R9, |
| UniProt Related Accession: | Q96IZ7 |
| Molecular Weight: | 334 |
| NCBI Full Name: | Serine/Arginine-related protein 53 |
| NCBI Synonym Full Names: | arginine/serine-rich coiled-coil 1 |
| NCBI Official Symbol: | RSRC1 |
| NCBI Official Synonym Symbols: | BM-011; SFRS21; SRrp53 |
| NCBI Protein Information: | serine/Arginine-related protein 53; splicing factor, arginine/serine-rich 21; arginine/serine-rich coiled-coil protein 1 |
| UniProt Protein Name: | Serine/Arginine-related protein 53 |
| UniProt Synonym Protein Names: | Arginine/serine-rich coiled-coil protein 1 |
| Protein Family: | Serine/Arginine-related protein |
| UniProt Gene Name: | RSRC1 |
| UniProt Entry Name: | RSRC1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RSRC1 antibody (CAB7210) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat testis using RSRC1 antibody (CAB7210) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human breast cancer using RSRC1 antibody (CAB7210) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse brain using RSRC1 antibody (CAB7210) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of MCF-7 cells using RSRC1 antibody (CAB7210). |
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