Description
| Product Name: | RRAS Rabbit pAb |
| Product Code: | CAB20243 |
| Size: | 50uL, 100uL |
| Synonyms: | RRAS |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human RRAS |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Immunogen: | Recombinant protein of human RRAS |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6237 |
| Uniprot: | P10301 |
| Cellular Location: | Cell membrane, Cytoplasmic side, Lipid-anchor |
| Calculated MW: | 23kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | RRas: a small G protein of the Ras family. Promotes focal adhesion formation by signaling to FAK and p130(Cas). Promotes tumor growth of cervical epithelial cells and increases their migration potential over collagen through a pathway that involves PI 3-K. |
| UniProt Protein Details: | Protein type:G protein, monomeric, Ras; Motility/polarity/chemotaxis; G protein, monomeric; G protein Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: focal adhesion; plasma membrane Molecular Function:GDP binding; GTPase activity; protein binding; protein complex binding Biological Process: leukocyte differentiation; positive regulation of angiogenesis; Ras protein signal transduction; regulation of protein kinase B signaling cascade |
| NCBI Summary: | The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015] |
| UniProt Code: | P10301 |
| NCBI GenInfo Identifier: | 133486 |
| NCBI Gene ID: | 6237 |
| NCBI Accession: | P10301.1 |
| UniProt Secondary Accession: | P10301,Q6FH12, |
| UniProt Related Accession: | P10301 |
| Molecular Weight: | 23,480 Da |
| NCBI Full Name: | Ras-related protein R-Ras |
| NCBI Synonym Full Names: | related RAS viral (r-ras) oncogene homolog |
| NCBI Official Symbol: | RRAS |
| NCBI Protein Information: | ras-related protein R-Ras |
| UniProt Protein Name: | Ras-related protein R-Ras |
| UniProt Synonym Protein Names: | p23 |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RRAS |
| UniProt Entry Name: | RRAS_HUMAN |