Epigenetics & Nuclear Signaling Antibodies 3
Anti-RPUSD3 Antibody (CAB14462)
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- SKU:
- CAB14462
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-RPUSD3 Antibody |
| Antibody SKU: | CAB14462 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-351 of human RPUSD3 (NP_775930.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-351 of human RPUSD3 (NP_775930.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PEDA GFGT EARH QRQP RGSC QRSG PLGD QPFA GLLP KNLS REEL VDAL RAAV VDRK GPLV TLNK PQGL PVTG KPGE LTLF SVLP ELSQ SLGL REQE LQVV RASG KESS GLVL LSSC PQTA SRLQ KYFT HARR AQRP TATY CAVT DGIP AASE GKIQ AALK LEHI DGVN LTVP VKAP SRKD ILEG VKKT LSHF RVVA TGSG CALV QLQP LTVF SSQL QVHM VLQL CPVL GDHM YSAR VGTV LGQR FLLP AENN KPQR QVLD EALL RRLH LTPS QAAQ LPLH LHLH RLLL PGTR ARDT PVEL LAPL PPYF SRTL QCLG LRLQ |
| Gene ID: | 285367 |
| Uniprot: | Q6P087 |
| Cellular Location: | |
| Calculated MW: | 14kDa/36kDa/38kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | RPUSD3 |
| Background: |
| UniProt Protein Function: | Major enzyme responsible for the conversion of uridine to pseudouridine (PSI) at position 390 in mitochondrial COXI (MT-CO1) mRNA and at position 697-699 in mitochondrial COXIII (MT-CO3) mRNA, modulating the efficiency of mitochondrial protein synthesis without changes in transcript abundance or stability. |
| NCBI Summary: | This gene encodes a protein that functions in the assembly of the mitochondrial ribosome by adding a pseudouridine group to 16S rRNA. Loss of this gene results in causes defects in mitochondrial protein production. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2017] |
| UniProt Code: | Q6P087 |
| NCBI GenInfo Identifier: | 41388986 |
| NCBI Gene ID: | 285367 |
| NCBI Accession: | BC065741 |
| UniProt Secondary Accession: | Q6P087,Q6P6A9, Q8N1B2, Q8NAV3, B4DS39, |
| UniProt Related Accession: | Q6P087 |
| Molecular Weight: | 14,887 Da |
| NCBI Full Name: | Homo sapiens RNA pseudouridylate synthase domain containing 3, mRNA |
| NCBI Synonym Full Names: | RNA pseudouridylate synthase domain containing 3 |
| NCBI Official Symbol: | RPUSD3 |
| NCBI Protein Information: | mitochondrial mRNA pseudouridine synthase RPUSD3 |
| UniProt Protein Name: | Mitochondrial mRNA pseudouridine synthase RPUSD3 |
| UniProt Synonym Protein Names: | RNA pseudouridylate synthase domain-containing protein 3 |
| Protein Family: | RNA pseudouridylate synthase domain-containing protein |
| UniProt Gene Name: | RPUSD3 |
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