Cell Biology Antibodies 18

Anti-RPS8 Antibody (CAB18377)

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SKU:
CAB18377
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-RPS8 Antibody
Antibody SKU:CAB18377
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human RPS8.
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:SGC-7901, HeLa, Mouse pancreas, Mouse ovary, Rat pancreas
Immunogen:Recombinant protein of human RPS8.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:6202
Uniprot:P62241
Cellular Location:
Calculated MW:24kDa
Observed MW:24kDa
Anti-RPS8 Antibody (CAB18377)Western blot - RPS8 Rabbit pAb (CAB18377)
Synonyms:S8, RPS8
Background:Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed. This gene is co-transcribed with the small nucleolar RNA genes U38A, U38B, U39, and U40, which are located in its fourth, fifth, first, and second introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
UniProt Protein Function:RPS8: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed. This gene is co-transcribed with the small nucleolar RNA genes U38A, U38B, U39, and U40, which are located in its fourth, fifth, first, and second introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Ribosomal; Translation

Chromosomal Location of Human Ortholog: 1p34.1-p32

Cellular Component: focal adhesion; membrane; cytoplasm; ribonucleoprotein complex; cytosol; nucleus

Molecular Function:structural constituent of ribosome

Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); SRP-dependent cotranslational protein targeting to membrane; translational elongation; cellular protein metabolic process; translation; viral reproduction; mRNA catabolic process, nonsense-mediated decay; translational initiation; gene expression; viral transcription; translational termination; viral infectious cycle

UniProt Code:P62241
NCBI GenInfo Identifier:4506743
NCBI Gene ID:6202
NCBI Accession:NP_001003
UniProt Secondary Accession:P62241,P09058, Q6IRL7,
UniProt Related Accession:P62241
Molecular Weight:24,205 Da
NCBI Full Name:40S ribosomal protein S8
NCBI Synonym Full Names:ribosomal protein S8
NCBI Official Symbol:RPS8  
NCBI Official Synonym Symbols:S8  
NCBI Protein Information:40S ribosomal protein S8; OK/SW-cl.83
UniProt Protein Name:40S ribosomal protein S8
Protein Family:30S ribosomal protein
UniProt Gene Name:RPS8  
UniProt Entry Name:RS8_HUMAN
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