UniProt Protein Function: | Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:28257692, PubMed:23636399, PubMed:25957688, PubMed:25901680). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:23636399, PubMed:25957688, PubMed:25901680). Plays an important role in translational accuracy (PubMed:28257692). |
NCBI Summary: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12P family of ribosomal proteins. It is located in the cytoplasm. The protein shares significant amino acid similarity with S. cerevisiae ribosomal protein S28. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
UniProt Code: | P62266 |
NCBI GenInfo Identifier: | 50403755 |
NCBI Gene ID: | 6228 |
NCBI Accession: | P62266.3 |
UniProt Secondary Accession: | P62266,P39028, Q6IB08, |
UniProt Related Accession: | P62266 |
Molecular Weight: | 15,808 Da |
NCBI Full Name: | 40S ribosomal protein S23 |
NCBI Synonym Full Names: | ribosomal protein S23 |
NCBI Official Symbol: | RPS23 |
NCBI Official Synonym Symbols: | S23; BTDD; uS12; MABAS; MCINS; PAMAS |
NCBI Protein Information: | 40S ribosomal protein S23 |
UniProt Protein Name: | 40S ribosomal protein S23 |
UniProt Synonym Protein Names: | Small ribosomal subunit protein uS12 |
Protein Family: | 40S ribosomal protein |
UniProt Gene Name: | RPS23 |