Cell Biology Antibodies 3
Anti-RPS19BP1 Antibody (CAB13231)
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- SKU:
- CAB13231
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RPS19BP1 Antibody |
| Antibody SKU: | CAB13231 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human RPS19BP1 (NP_919307.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, A-431, Jurkat, MCF7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human RPS19BP1 (NP_919307.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSAA LLRR GLEL LAAS EAPR DPPG QAKP RGAP VKRP RKTK AIQA QKLR NSAK GKVP KSAL DEYR KREC RDHL RVNL KFLT RTRS TVAE SVSQ QILR QNRG RKAC DRPV AKTK KKKA EGTV FTEE DFQK FQQE YFGS |
| Gene ID: | 91582 |
| Uniprot: | Q86WX3 |
| Cellular Location: | Nucleus, nucleolus |
| Calculated MW: | 15kDa |
| Observed MW: | 20kDa |
| Synonyms: | RPS19BP1, AROS, S19BP |
| Background: |
| UniProt Protein Function: | RPS19BP1: Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity. Belongs to the AROS family. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: cytoplasm; nucleolus; nucleoplasm Molecular Function:enzyme binding; protein binding |
| UniProt Code: | Q86WX3 |
| NCBI GenInfo Identifier: | 74727734 |
| NCBI Gene ID: | 91582 |
| NCBI Accession: | Q86WX3.1 |
| UniProt Secondary Accession: | Q86WX3,Q5JZA1, B0QY96, |
| UniProt Related Accession: | Q86WX3 |
| Molecular Weight: | 15,434 Da |
| NCBI Full Name: | Active regulator of SIRT1 |
| NCBI Synonym Full Names: | ribosomal protein S19 binding protein 1 |
| NCBI Official Symbol: | RPS19BP1 |
| NCBI Official Synonym Symbols: | AROS; S19BP |
| NCBI Protein Information: | active regulator of SIRT1 |
| UniProt Protein Name: | Active regulator of SIRT1 |
| UniProt Synonym Protein Names: | 40S ribosomal protein S19-binding protein 1; RPS19-binding protein 1; S19BP |
| UniProt Gene Name: | RPS19BP1 |
| UniProt Entry Name: | AROS_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RPS19BP1 antibody (CAB13231) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunofluorescence analysis of L929 cells using RPS19BP1 antibody (CAB13231) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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