Anti-RPL7A Antibody (CAB19247)
- SKU:
- CAB19247
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- RPL7A
- Synonyms:
- L7A
- Synonyms:
- SURF3
- Synonyms:
- TRUP
- Synonyms:
- ribosomal protein L7a
- Research Area:
- Cell Biology
Description
| Product Name: | RPL7A Rabbit mAb |
| Product Code: | CAB19247 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | RPL7A, L7A, SURF3, TRUP, ribosomal protein L7a |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human RPL7A. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant protein of human RPL7A. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6130 |
| Uniprot: | P62424 |
| Calculated MW: | 30kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | RPL7A: Belongs to the ribosomal protein L7Ae family. |
| UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Translation; Ribosomal Chromosomal Location of Human Ortholog: 9q34 Cellular Component: cytoplasm; cytosol; focal adhesion; membrane; nucleolus; nucleus; polysomal ribosome Molecular Function:protein binding; RNA binding Biological Process: maturation of LSU-rRNA; mRNA catabolic process, nonsense-mediated decay; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translational initiation; viral transcription |
| NCBI Summary: | Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P62424 |
| NCBI GenInfo Identifier: | 54039239 |
| NCBI Gene ID: | 6130 |
| NCBI Accession: | P62424.2 |
| UniProt Secondary Accession: | P62424,P11518, Q5T8U4, |
| UniProt Related Accession: | P62424 |
| Molecular Weight: | 29,996 Da |
| NCBI Full Name: | 60S ribosomal protein L7a |
| NCBI Synonym Full Names: | ribosomal protein L7a |
| NCBI Official Symbol: | RPL7A |
| NCBI Official Synonym Symbols: | L7A; TRUP; SURF3 |
| NCBI Protein Information: | 60S ribosomal protein L7a |
| UniProt Protein Name: | 60S ribosomal protein L7a |
| UniProt Synonym Protein Names: | PLA-X polypeptide; Surfeit locus protein 3 |
| Protein Family: | 60S ribosomal protein |
| UniProt Gene Name: | RPL7A |
| UniProt Entry Name: | RL7A_HUMAN |
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