Cell Biology Antibodies 5

Anti-RPL6 Antibody (CAB15094)

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SKU:
CAB15094
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-RPL6 Antibody
Antibody SKU:CAB15094
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 188-288 of human RPL6 (NP_000961.2).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, LO2, A549, HeLa, mouse liver, rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 188-288 of human RPL6 (NP_000961.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RTHQ KFVI ATST KIDI SNVK IPKH LTDA YFKK KKLR KPRH QEGE IFDT EKEK YEIT EQRK IDQK AVDS QILP KIKA IPQL QGYL RSVF ALTN GIYP HKLV F
Gene ID:6128
Uniprot:Q02878
Cellular Location:
Calculated MW:32kDa
Observed MW:38kDa
Synonyms:RPL6, L6, SHUJUN-2, TAXREB107, TXREB1
Background:This gene encodes a protein component of the 60S ribosomal subunit. This protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:RPL6: Specifically binds to domain C of the Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Belongs to the ribosomal protein L6e family.
UniProt Protein Details:

Protein type:Translation

Chromosomal Location of Human Ortholog: 12q24.1

Cellular Component: cytosol; focal adhesion; membrane; nucleus

Molecular Function:DNA binding; RNA binding

Biological Process: mRNA catabolic process, nonsense-mediated decay; regulation of transcription, DNA-dependent; ribosomal large subunit assembly and maintenance; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translational initiation; viral transcription

NCBI Summary:This gene encodes a protein component of the 60S ribosomal subunit. This protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
UniProt Code:Q02878
NCBI GenInfo Identifier:1350762
NCBI Gene ID:6128
NCBI Accession:Q02878.3
UniProt Secondary Accession:Q02878,Q2M3Q3, Q8WW97,
UniProt Related Accession:Q02878
Molecular Weight:32,728 Da
NCBI Full Name:60S ribosomal protein L6
NCBI Synonym Full Names:ribosomal protein L6
NCBI Official Symbol:RPL6  
NCBI Official Synonym Symbols:L6; TXREB1; SHUJUN-2; TAXREB107  
NCBI Protein Information:60S ribosomal protein L6
UniProt Protein Name:60S ribosomal protein L6
UniProt Synonym Protein Names:Neoplasm-related protein C140; Tax-responsive enhancer element-binding protein 107; TaxREB107
Protein Family:50S ribosomal protein
UniProt Gene Name:RPL6  
UniProt Entry Name:RL6_HUMAN
Anti-RPL6 Antibody (CAB15094)Western blot analysis of extracts of various cell lines, using RPL6 antibody (CAB15094) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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