Cardiovascular Antibodies
Anti-ROBO4 Antibody (CAB9876)
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- SKU:
- CAB9876
Description
| Antibody Name: | Anti-ROBO4 Antibody |
| Antibody SKU: | CAB9876 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 848-1007 of human ROBO4 (NP_061928.4). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HT-29, HepG2, HT-1080, HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 848-1007 of human ROBO4 (NP_061928.4). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GVGP KGGV LLCP PRPC LTPT PSEG SLAN GWGS ASED NAAS ARAS LVSS SDGS FLAD AHFA RALA VAVD SFGF GLEP READ CVFI DASS PPSP RDEI FLTP NLSL PLWE WRPD WLED MEVS HTQR LGRG MPPW PPDS QISS QRSQ LHCR MPKA GASP VDYS |
| Gene ID: | 54538 |
| Uniprot: | Q8WZ75 |
| Cellular Location: | |
| Calculated MW: | 75kDa/98kDa/107kDa |
| Observed MW: | 130kDa |
| Synonyms: | ROBO4, ECSM4, MRB |
| Background: |
| UniProt Protein Function: | ROBO4: Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Belongs to the immunoglobulin superfamily. ROBO family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 11q24.2 Cellular Component: integral to membrane Molecular Function:receptor activity Biological Process: angiogenesis; regulation of apoptosis |
| UniProt Code: | Q8WZ75 |
| NCBI GenInfo Identifier: | 49036490 |
| NCBI Gene ID: | 54538 |
| NCBI Accession: | Q8WZ75.1 |
| UniProt Secondary Accession: | Q8WZ75,Q14DU7, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8, A8K154 |
| UniProt Related Accession: | Q8WZ75 |
| Molecular Weight: | 75,282 Da |
| NCBI Full Name: | Roundabout homolog 4 |
| NCBI Synonym Full Names: | roundabout guidance receptor 4 |
| NCBI Official Symbol: | ROBO4 |
| NCBI Official Synonym Symbols: | MRB; ECSM4 |
| NCBI Protein Information: | roundabout homolog 4 |
| UniProt Protein Name: | Roundabout homolog 4 |
| UniProt Synonym Protein Names: | Magic roundabout |
| Protein Family: | Roundabout |
| UniProt Gene Name: | ROBO4 |
| UniProt Entry Name: | ROBO4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ROBO4 antibody (CAB9876) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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Additional Information
Product Type: |
Antibody |
Applications: |
WB |
Reactivity: |
Human |
Host Species: |
Rabbit |
Isotype: |
IgG |
Research Area: |
Cardiovascular |
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