Cell Biology Antibodies 13
Anti-RNF38 Antibody (CAB17263)
- SKU:
- CAB17263
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-RNF38 Antibody |
Antibody SKU: | CAB17263 |
Antibody Size: | 20uL, 50 uL |
Application: | WB |
Reactivity: | Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-90 of human RNF38 (NP_073618.3). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Rat |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-90 of human RNF38 (NP_073618.3). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | NSAS LPGH PNKV ICER VRLQ SLFP LLPS DQNT TVQE DAHF KAFF QSED SPSP KRQR LSHS VFDY TSAS PAPS PPMR PWEM T |
Gene ID: | 152006 |
Uniprot: | Q9H0F5 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | Refer to figures |
Synonyms: | RNF38 |
Background: | This gene encodes a protein with a coiled-coil motif and a RING-H2 motif (C3H2C2) at its carboxy-terminus. The RING motif is a zinc-binding domain found in a large set of proteins playing roles in diverse cellular processes including oncogenesis, development, signal transduction, and apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | Acts as an E3 ubiquitin-protein ligase able to ubiquitinate p53/TP53 which promotes its relocalization to discrete foci associated with PML nuclear bodies. Exhibits preference for UBE2D2 as a E2 enzyme. |
NCBI Summary: | This gene encodes a protein with a coiled-coil motif and a RING-H2 motif (C3H2C2) at its carboxy-terminus. The RING motif is a zinc-binding domain found in a large set of proteins playing roles in diverse cellular processes including oncogenesis, development, signal transduction, and apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
UniProt Code: | Q9H0F5 |
NCBI GenInfo Identifier: | 56749664 |
NCBI Gene ID: | 152006 |
NCBI Accession: | Q9H0F5.4 |
UniProt Secondary Accession: | Q9H0F5,Q7LB33, Q8N0Y0, Q9H748, A6PVP9, B1AM81, B1AM82 B3KSG4, E7EVL3, |
UniProt Related Accession: | Q9H0F5 |
Molecular Weight: | 36,836 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase RNF38 |
NCBI Synonym Full Names: | ring finger protein 38 |
NCBI Official Symbol: | RNF38 |
NCBI Protein Information: | E3 ubiquitin-protein ligase RNF38 |
UniProt Protein Name: | E3 ubiquitin-protein ligase RNF38 |
UniProt Synonym Protein Names: | RING finger protein 38 |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | RNF38 |
UniProt Entry Name: | RNF38_HUMAN |