Cell Biology Antibodies 16

Anti-Rnf170 Antibody (CAB15196)

(No reviews yet) Write a Review
SKU:
CAB15196
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-Rnf170 Antibody
Antibody SKU:CAB15196
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of mouse Rnf170 (NP_084241.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse pancreas, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of mouse Rnf170 (NP_084241.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MQRY WRFQ DNKI QDIC FGVL GESW IQRP VMAR YYSE GQSL QQDD SFIE GVSD QVLV AVVV SLAL TATL LYAL LRNV QQNI HPEN QELV RVLR EQFQ TEQD VPAP ARQQ FYTE MYCP ICLH QASF PVET NCGH LFCG SCII AYWR YGSW LGAI SCPI CRQT VTLL LTVF GEDD QSQD VIRL RQDV NDYN RRFS GQPR SIME
Gene ID:77733
Uniprot:
Cellular Location:Endoplasmic reticulum membrane, Multi-pass membrane protein
Calculated MW:16kDa/24kDa/28kDa/33kDa
Observed MW:28kDa
Synonyms:RNF170, ADSA, SNAX1, Rnf170
Background:This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1, 4, 5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene.
Anti-Rnf170 Antibody (CAB15196)Western blot analysis of extracts of various cell lines, using Rnf170 antibody (CAB15196) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
View AllClose

0 Reviews

View AllClose

Related Products