Cell Biology Antibodies 5
Anti-RNASE6 Antibody (CAB15312)
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- SKU:
- CAB15312
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RNASE6 Antibody |
| Antibody SKU: | CAB15312 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human RNASE6 (NP_005606.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human RNASE6 (NP_005606.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MVLC FPLL LLLL VLWG PVCP LHAW PKRL TKAH WFEI QHIQ PSPL QCNR AMSG INNY TQHC KHQN TFLH DSFQ NVAA VCDL LSIV CKNR RHNC HQSS KPVN MTDC RLTS GKYP QCRY SAAA QYKF FIVA CDPP QKSD PPYK LVPV HLDS IL |
| Gene ID: | 6039 |
| Uniprot: | Q93091 |
| Cellular Location: | Secreted |
| Calculated MW: | 17kDa |
| Observed MW: | 17kDa |
| Synonyms: | RNASE6, RAD1, RNS6, RNasek6 |
| Background: | The protein encoded by this gene is a member of the ribonuclease A superfamily and functions in the urinary tract. The protein has broad-spectrum antimicrobial activity against pathogenic bacteria. |
| UniProt Protein Function: | RNASE6: May have a role in host defense. Belongs to the pancreatic ribonuclease family. |
| UniProt Protein Details: | Protein type:Secreted; EC 3.1.27.-; Ribonuclease; Secreted, signal peptide Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: extracellular region Molecular Function:endonuclease activity; ribonuclease activity Biological Process: defense response; RNA catabolic process |
| NCBI Summary: | The protein encoded by this gene is a member of the ribonuclease A superfamily and functions in the urinary tract. The protein has broad-spectrum antimicrobial activity against pathogenic bacteria. [provided by RefSeq, Nov 2014] |
| UniProt Code: | Q93091 |
| NCBI GenInfo Identifier: | 3123285 |
| NCBI Gene ID: | 6039 |
| NCBI Accession: | Q93091.2 |
| UniProt Related Accession: | Q93091 |
| Molecular Weight: | 17,196 Da |
| NCBI Full Name: | Ribonuclease K6 |
| NCBI Synonym Full Names: | ribonuclease A family member k6 |
| NCBI Official Symbol: | RNASE6 |
| NCBI Official Synonym Symbols: | RAD1; RNS6; RNasek6 |
| NCBI Protein Information: | ribonuclease K6 |
| UniProt Protein Name: | Ribonuclease K6 |
| Protein Family: | Ribonuclease |
| UniProt Gene Name: | RNASE6 |
| UniProt Entry Name: | RNAS6_HUMAN |
 | Western blot analysis of extracts of Mouse kidney, using RNASE6 antibody (CAB15312) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human lung cancer using RNASE6 antibody (CAB15312) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human appendix using RNASE6 antibody (CAB15312) at dilution of 1:100 (40x lens). |
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