Cell Biology Antibodies 12
Anti-RNASE2 Antibody (CAB9949)
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- SKU:
- CAB9949
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RNASE2 Antibody |
| Antibody SKU: | CAB9949 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-161 of human RNASE2 (NP_002925.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | K-562, HL-60, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-161 of human RNASE2 (NP_002925.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KPPQ FTWA QWFE TQHI NMTS QQCT NAMQ VINN YQRR CKNQ NTFL LTTF ANVV NVCG NPNM TCPS NKTR KNCH HSGS QVPL IHCN LTTP SPQN ISNC RYAQ TPAN MFYI VACD NRDQ RRDP PQYP VVPV HLDR II |
| Gene ID: | 6036 |
| Uniprot: | P10153 |
| Cellular Location: | Cytoplasmic granule, Lysosome |
| Calculated MW: | 18kDa |
| Observed MW: | 26kDa |
| Synonyms: | RNASE2, EDN, RAF3, RNS2 |
| Background: | The protein encoded by this gene is a non-secretory ribonuclease that belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein antimicrobial activity against viruses. |
| UniProt Protein Function: | RNASE2: This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. Belongs to the pancreatic ribonuclease family. |
| UniProt Protein Details: | Protein type:RNA processing; Motility/polarity/chemotaxis; Ribonuclease; EC 3.1.27.5 Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: extracellular region Molecular Function:endonuclease activity; ribonuclease activity Biological Process: chemotaxis; RNA catabolic process |
| NCBI Summary: | The protein encoded by this gene is a non-secretory ribonuclease that belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein antimicrobial activity against viruses. [provided by RefSeq, Oct 2014] |
| UniProt Code: | P10153 |
| NCBI GenInfo Identifier: | 133168 |
| NCBI Gene ID: | 6036 |
| NCBI Accession: | P10153.2 |
| UniProt Secondary Accession: | P10153,Q52M39, Q9H2B7, Q9UCG7, |
| UniProt Related Accession: | P10153 |
| Molecular Weight: | 18,354 Da |
| NCBI Full Name: | Non-secretory ribonuclease |
| NCBI Synonym Full Names: | ribonuclease A family member 2 |
| NCBI Official Symbol: | RNASE2 |
| NCBI Official Synonym Symbols: | EDN; RAF3; RNS2 |
| NCBI Protein Information: | non-secretory ribonuclease |
| UniProt Protein Name: | Non-secretory ribonuclease |
| UniProt Synonym Protein Names: | Eosinophil-derived neurotoxin; RNase UpI-2; Ribonuclease 2; RNase 2; Ribonuclease US |
| Protein Family: | Non-secretory ribonuclease |
| UniProt Gene Name: | RNASE2 |
| UniProt Entry Name: | RNAS2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RNASE2 antibody (CAB9949) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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