Epigenetics & Nuclear Signaling Antibodies 3
Anti-RMI1 Antibody (CAB4991)
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- SKU:
- CAB4991
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- RMI1
- Synonyms:
- BLAP75
- Synonyms:
- C9orf76
- Synonyms:
- FAAP75
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | RMI1 Rabbit pAb |
| Product Code: | CAB4991 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | RMI1, BLAP75, C9orf76, FAAP75 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RMI1 (NP_079221.2). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RMI1 (NP_079221.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MNVT SIAL RAET WLLA AWHV KVPP MWLE ACIN WIQE ENNN VNLS QAQM NKQV FEQW LLTD LRDL EHPL LPDG ILEI PKGE LNGF YALQ INSL VDVS QPAY SQIQ KLRG KNTT NDLV TAEA QVTP KPWE AKPS RMLM LQLT DGIV QIQG MEYQ PIPI LHSD LPPG TKIL IYGN ISFR LGVL LLKP ENVK VLGG EVDA LLEE YAQE KVLA RLIG EPDL VVSV IPNN SNEN IPRV TDVL DPAL GPSD EELL ASLD ENDE LTAN NDTS SERC FTTG SSSN TIPT RQSS FEPE FVIS PRPK EEPS NLSI HVMD GELD DFSL EEAL LLEE TVQK EQME TKEL QPLT FNRN ADRS IE |
| Gene ID: | 80010 |
| Uniprot: | Q9H9A7 |
| Cellular Location: | Nucleus |
| Calculated MW: | 70kDa |
| Observed MW: | 75kDa |
| UniProt Protein Function: | RMI1: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability. Belongs to the RMI1 family. |
| UniProt Protein Details: | Protein type:DNA repair, damage Chromosomal Location of Human Ortholog: 9q21.32 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding Biological Process: multicellular organism growth; response to glucose stimulus; DNA replication; glucose homeostasis; reduction of food intake in response to dietary excess |
| NCBI Summary: | RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9H9A7 |
| NCBI GenInfo Identifier: | 322510109 |
| NCBI Gene ID: | 80010 |
| NCBI Accession: | Q9H9A7.3 |
| UniProt Secondary Accession: | Q9H9A7,Q05BX1, Q05CW3, Q5SQG8, Q5SQG9, Q6P1Q4, Q6PI89 Q7Z6L6, |
| UniProt Related Accession: | Q9H9A7 |
| Molecular Weight: | 625 |
| NCBI Full Name: | RecQ-mediated genome instability protein 1 |
| NCBI Synonym Full Names: | RecQ mediated genome instability 1 |
| NCBI Official Symbol: | RMI1 |
| NCBI Official Synonym Symbols: | BLAP75; FAAP75; C9orf76 |
| NCBI Protein Information: | recQ-mediated genome instability protein 1; BLM-associated protein 75 kDa; BLM-associated polypeptide, 75 kDa; RMI1, RecQ mediated genome instability 1, homolog; homolog of yeast RecQ-mediated genome instability 1 (RMI1) |
| UniProt Protein Name: | RecQ-mediated genome instability protein 1 |
| UniProt Synonym Protein Names: | BLM-associated protein of 75 kDa; BLAP75; FAAP75 |
| Protein Family: | RecQ-mediated genome instability protein |
| UniProt Gene Name: | RMI1 |
| UniProt Entry Name: | RMI1_HUMAN |
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