Cell Biology Antibodies 3

Anti-RIPK4 Antibody (CAB12580)

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SKU:
CAB12580
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-RIPK4 Antibody
Antibody SKU:CAB12580
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 240-520 of human RIPK4 (NP_065690.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:100 - 1:200
Reactivity:Human, Rat
Positive Samples:Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 240-520 of human RIPK4 (NP_065690.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:HRPE LPPV CRAR PRAC SHLI RLMQ RCWQ GDPR VRPT FQEI TSET EDLC EKPD DEVK ETAH DLDV KSPP EPRS EVVP ARLK RASA PTFD NDYS LSEL LSQL DSGV SQAV EGPE ELSR SSSE SKLP SSGS GKRL SGVS SVDS AFSS RGSL SLSF EREP STSD LGTT DVQK KKLV DAIV SGDT SKLM KILQ PQDV DLAL DSGA SLLH LAVE AGQE ECAK WLLL NNAN PNLS NRRG STPL HMAV ERRV RGVV ELLL ARKI SVNA KDED QWTA LHFA AQNG DESS T
Gene ID:54101
Uniprot:P57078
Cellular Location:Cytoplasm, Membrane, Peripheral membrane protein
Calculated MW:86kDa/91kDa
Observed MW:90kDa
Synonyms:RIPK4, ANKK2, ANKRD3, DIK, NKRD3, PKK, PPS2, RIP4
Background:The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
UniProt Protein Function:Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.
NCBI Summary:The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008]
UniProt Code:P57078
NCBI GenInfo Identifier:10719883
NCBI Gene ID:54101
NCBI Accession:P57078.1
UniProt Secondary Accession:P57078,Q96KH0,
UniProt Related Accession:P57078
Molecular Weight:Calculated: 86kDa; 91kDaObserved: 85kDa
NCBI Full Name:Receptor-interacting serine/threonine-protein kinase 4
NCBI Synonym Full Names:receptor interacting serine/threonine kinase 4
NCBI Official Symbol:RIPK4  
NCBI Official Synonym Symbols:DIK; PKK; PPS2; RIP4; ANKK2; NKRD3; ANKRD3; CHANDS  
NCBI Protein Information:receptor-interacting serine/threonine-protein kinase 4
UniProt Protein Name:Receptor-interacting serine/threonine-protein kinase 4
UniProt Synonym Protein Names:Ankyrin repeat domain-containing protein 3; PKC-delta-interacting protein kinase
Protein Family:Receptor-interacting serine/threonine-protein kinase
UniProt Gene Name:RIPK4  
Anti-RIPK4 Antibody (CAB12580)Western blot analysis of extracts of rat brain, using RIPK4 antibody (CAB12580) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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