Immunology Antibodies 2
Anti-RIOK3 Antibody (CAB15744)
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- SKU:
- CAB15744
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-RIOK3 Antibody |
| Antibody SKU: | CAB15744 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-519 of human RIOK3 (NP_003822.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | U-251MG, Mouse pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-519 of human RIOK3 (NP_003822.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NHVF NALK QHAY SEER RSAR LHEK KEHS TAEK AVDP KTRL LMYK MVNS GMLE TITG CIST GKES VVFH AYGG SMED EKED SKVI PTEC AIKV FKTT LNEF KNRD KYIK DDFR FKDR FSKL NPRK IIRM WAEK EMHN LARM QRAG IPCP TVVL LKKH ILVM SFIG HDQV PAPK LKEV KLNS EEMK EAYY QTLH LMRQ LYHE CTLV HADL SEYN MLWH AGKV WLID VSQS VEPT HPHG LEFL FRDC RNVS QFFQ KGGV KEAL SERE LFNA VSGL NITA DNEA DFLA EIEA LEKM NEDH VQKN GRKA ASFL KDDG DPPL LYDE |
| Gene ID: | 8780 |
| Uniprot: | O14730 |
| Cellular Location: | |
| Calculated MW: | 58kDa/59kDa |
| Observed MW: | 70kDa |
| Synonyms: | RIOK3, SUDD |
| Background: | This gene was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. The specific function of this gene has not yet been determined. |
| UniProt Protein Function: | RIOK3: identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. The specific function of this gene has not yet been determined. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Protein kinase, atypical; Kinase, protein; EC 2.7.11.1; ATYPICAL group; RIO family; RIO3 subfamily Chromosomal Location of Human Ortholog: 18q11.2 Molecular Function:protein serine/threonine kinase activity; protein binding; ATP binding Biological Process: protein amino acid phosphorylation; chromosome segregation |
| NCBI Summary: | This gene was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. The specific function of this gene has not yet been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O14730 |
| NCBI GenInfo Identifier: | 126302595 |
| NCBI Gene ID: | 8780 |
| NCBI Accession: | O14730.2 |
| UniProt Secondary Accession: | O14730,Q8IXN9, |
| UniProt Related Accession: | O14730 |
| Molecular Weight: | 519 |
| NCBI Full Name: | Serine/threonine-protein kinase RIO3 |
| NCBI Synonym Full Names: | RIO kinase 3 |
| NCBI Official Symbol: | RIOK3 |
| NCBI Official Synonym Symbols: | SUDD |
| NCBI Protein Information: | serine/threonine-protein kinase RIO3; sudD homolog; sudD suppressor of bimD6 homolog; homolog of the Aspergillus nidulans sudD gene product; sudD suppressor of Aspergillus nidulans bimD6 homolog; sudD (suppressor of bimD6, Aspergillus nidulans) homolog |
| UniProt Protein Name: | Serine/threonine-protein kinase RIO3 |
| UniProt Synonym Protein Names: | RIO kinase 3; sudD homolog |
| UniProt Gene Name: | RIOK3 |
| UniProt Entry Name: | RIOK3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RIOK3 antibody (CAB15744) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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