Cell Biology Antibodies 7

Anti-RHOU Antibody (CAB17194)

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SKU:
CAB17194
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-RHOU Antibody
Antibody SKU:CAB17194
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide of human RHOU.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:A synthetic peptide of human RHOU.
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:58480
Uniprot:Q7L0Q8
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:RHOU, ARHU, CDC42L1, G28K, WRCH1, hG28K
Background:This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.
UniProt Protein Function:Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
NCBI Summary:This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011]
UniProt Code:Q7L0Q8
NCBI GenInfo Identifier:11034843
NCBI Gene ID:58480
NCBI Accession:NP_067028.1
UniProt Secondary Accession:Q7L0Q8,Q59FE9, Q8TDQ2, B1AKN1,
UniProt Related Accession:Q7L0Q8
Molecular Weight:22,164 Da
NCBI Full Name:rho-related GTP-binding protein RhoU
NCBI Synonym Full Names:ras homolog family member U
NCBI Official Symbol:RHOU  
NCBI Official Synonym Symbols:ARHU; G28K; WRCH1; hG28K; CDC42L1  
NCBI Protein Information:rho-related GTP-binding protein RhoU
UniProt Protein Name:Rho-related GTP-binding protein RhoU
UniProt Synonym Protein Names:CDC42-like GTPase 1; GTP-binding protein-like 1; Rho GTPase-like protein ARHU; Ryu GTPase; Wnt-1 responsive Cdc42 homolog 1; WRCH-1
Protein Family:Rho-related GTP-binding protein
UniProt Gene Name:RHOU  
Anti-RHOU Antibody (CAB17194)Western blot analysis of extracts of U-87MG cells, using RHOU antibody (CAB17194) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s.
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