Anti-RhoGAP Antibody (CAB2330)
- SKU:
- CAB2330
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GFI2
- Synonyms:
- RhoGAP5
- Synonyms:
- p190-B
- Synonyms:
- p190BRhoGAP
- Research Area:
- Cell Biology
Description
| Product Name: | RhoGAP Rabbit mAb |
| Product Code: | CAB2330 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | GFI2, RhoGAP5, p190-B, p190BRhoGAP |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human RhoGAP |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, MCF7, C2C12, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human RhoGAP |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 394 |
| Uniprot: | Q13017 |
| Cellular Location: | Cytoplasm, Membrane, Peripheral membrane protein |
| Calculated MW: | 190kDa |
| Observed MW: | 190kDa |
| UniProt Protein Function: | ARHGAP5: a GTPase activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of p120GAP. Negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. |
| UniProt Protein Details: | Protein type:GAPs; Motility/polarity/chemotaxis; GAPs, Rac/Rho Chromosomal Location of Human Ortholog: 14q12 Cellular Component: membrane; cytoplasm; cytosol Molecular Function:GTPase activity; protein binding; GTP binding; SH2 domain binding Biological Process: regulation of small GTPase mediated signal transduction; mammary gland development; metabolic process; small GTPase mediated signal transduction; positive regulation of mesenchymal cell proliferation; cell adhesion; regulation of cell size; Rho protein signal transduction; positive regulation of cell migration |
| NCBI Summary: | Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13017 |
| NCBI GenInfo Identifier: | 190358871 |
| NCBI Gene ID: | 394 |
| NCBI Accession: | Q13017.2 |
| UniProt Related Accession: | Q13017 |
| Molecular Weight: | |
| NCBI Full Name: | Rho GTPase-activating protein 5 |
| NCBI Synonym Full Names: | Rho GTPase activating protein 5 |
| NCBI Official Symbol: | ARHGAP5 |
| NCBI Official Synonym Symbols: | GFI2; p190-B; RhoGAP5; p190BRhoGAP |
| NCBI Protein Information: | rho GTPase-activating protein 5 |
| UniProt Protein Name: | Rho GTPase-activating protein 5 |
| UniProt Synonym Protein Names: | Rho-type GTPase-activating protein 5; p190-B |
| UniProt Gene Name: | ARHGAP5 |
| UniProt Entry Name: | RHG05_HUMAN |
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