Cell Biology Antibodies 13
Anti-RHOBTB3 Antibody (CAB17638)
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- SKU:
- CAB17638
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RHOBTB3 Antibody |
| Antibody SKU: | CAB17638 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RHOBTB3 (NP_055714.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RHOBTB3 (NP_055714.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSIH IVAL GNEG DTFH QDNR PSGL IRTY LGRS PLVS GDES SLLL NAAS TVAR PVFT EYQA SAFG NVKL VVHD CPVW DIFD SDWY TSRN LIGG ADII VIKY NVND KFSF HEVK DNYI PVIK RALN SVPV IIAA VGTR QNEE LPCT CPLC TSDR GSCV STTE GIQL AKEL GATY LELH SLDD FYIG KYFG GVLE YFMI QALN QKTS EKMK KRKM SNSF HGIR PPQL EQPE KM |
| Gene ID: | 22836 |
| Uniprot: | O94955 |
| Cellular Location: | |
| Calculated MW: | 69kDa |
| Observed MW: | Refer to figures |
| Synonyms: | RHOBTB3 |
| Background: | RHOBTB3 is a member of the evolutionarily conserved RHOBTB subfamily of Rho GTPases. For background information on RHOBTBs, see RHOBTB1 (MIM 607351).[supplied by OMIM, Apr 2004] |
| UniProt Protein Function: | RHOBTB3: Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9. |
| UniProt Protein Details: | Protein type:Hydrolase; EC 3.6.1.- Chromosomal Location of Human Ortholog: 5q15 Cellular Component: Golgi apparatus Molecular Function:ATP binding; ATPase activity; protein binding; Rab GTPase binding Biological Process: metabolic process; retrograde transport, endosome to Golgi; small GTPase mediated signal transduction |
| NCBI Summary: | RHOBTB3 is a member of the evolutionarily conserved RHOBTB subfamily of Rho GTPases. For background information on RHOBTBs, see RHOBTB1 (MIM 607351).[supplied by OMIM, Apr 2004] |
| UniProt Code: | O94955 |
| NCBI GenInfo Identifier: | 125987856 |
| NCBI Gene ID: | 22836 |
| NCBI Accession: | O94955.2 |
| UniProt Secondary Accession: | O94955,Q8IW06, A0PJA4, A8K1W9, |
| UniProt Related Accession: | O94955 |
| Molecular Weight: | 69,413 Da |
| NCBI Full Name: | Rho-related BTB domain-containing protein 3 |
| NCBI Synonym Full Names: | Rho related BTB domain containing 3 |
| NCBI Official Symbol: | RHOBTB3 |
| NCBI Protein Information: | rho-related BTB domain-containing protein 3 |
| UniProt Protein Name: | Rho-related BTB domain-containing protein 3 |
| Protein Family: | Rho-related BTB domain-containing protein |
| UniProt Gene Name: | RHOBTB3 |
| UniProt Entry Name: | RHBT3_HUMAN |
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