Cell Biology Antibodies 18

Anti-RHOBTB2 Antibody (CAB18432)

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SKU:
CAB18432
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-RHOBTB2 Antibody
Antibody SKU:CAB18432
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human RHOBTB2.
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Rat lung
Immunogen:Recombinant protein of human RHOBTB2.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:23221
Uniprot:Q9BYZ6
Cellular Location:
Calculated MW:
Observed MW:83kDa
Anti-RHOBTB2 Antibody (CAB18432)Western blot - RHOBTB2 Rabbit pAb (CAB18432)
Synonyms:DBC2, RHOBTB2
Background:
UniProt Protein Function:RHOBTB2: is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
UniProt Protein Details:

Protein type:G protein; G protein, monomeric, Rho; G protein, monomeric

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: plasma membrane; cytosol

Molecular Function:GTP binding

Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction

NCBI Summary:The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
UniProt Code:Q9BYZ6
NCBI GenInfo Identifier:12667516
NCBI Gene ID:23221
NCBI Accession:AAG61157.1
UniProt Secondary Accession:Q9BYZ6,O94825, Q8N4A8, Q9BZK6, A8K9Z8, D3DSR8, E9PBU2 E9PEI7,
UniProt Related Accession:Q9BYZ6
Molecular Weight:83,469 Da
NCBI Full Name:DBC2
NCBI Synonym Full Names:Rho-related BTB domain containing 2
NCBI Official Symbol:RHOBTB2  
NCBI Official Synonym Symbols:DBC2  
NCBI Protein Information:rho-related BTB domain-containing protein 2; deleted in breast cancer 2 gene protein; p83
UniProt Protein Name:Rho-related BTB domain-containing protein 2
UniProt Synonym Protein Names:Deleted in breast cancer 2 gene protein; p83
UniProt Gene Name:RHOBTB2  
UniProt Entry Name:RHBT2_HUMAN
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