Signal Transduction Antibodies 2

Anti-RHCG Antibody (CAB16124)

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SKU:
CAB16124
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-RHCG Antibody
Antibody SKU:CAB16124
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 240-479 of human RHCG (NP_057405.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:BxPC-3, DU145, 293T, Mouse kidney, Rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 240-479 of human RHCG (NP_057405.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SYHG DSQH RAAI NTYC SLAA CVLT SVAI SSAL HKKG KLDM VHIQ NATL AGGV AVGT AAEM MLMP YGAL IIGF VCGI ISTL GFVY LTPF LESR LHIQ DTCG INNL HGIP GIIG GIVG AVTA ASAS LEVY GKEG LVHS FDFQ GFNG DWTA RTQG KFQI YGLL VTLA MALM GGII VGLI LRLP FWGQ PSDE NCFE DAVY WEMP EGNS TVYI PEDP TFKP SGPS VPSV PMVS PLPM ASSV PLVP
Gene ID:51458
Uniprot:Q9UBD6
Cellular Location:Apical cell membrane, Multi-pass membrane protein
Calculated MW:53kDa
Observed MW:53kDa
Synonyms:RHCG, C15orf6, PDRC2, RHGK, SLC42A3
Background:
UniProt Protein Function:RHCG: Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion. Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
UniProt Protein Details:

Protein type:Transporter, SLC family; Transporter; Membrane protein, multi-pass; Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q25

Cellular Component: integral to plasma membrane; basolateral plasma membrane; apical plasma membrane; plasma membrane; cytoplasmic vesicle

Molecular Function:ammonium transmembrane transporter activity; ankyrin binding

Biological Process: homeostatic process; epithelial cell differentiation; cellular ion homeostasis; amine transport; regulation of pH; transmembrane transport; ammonium transport

UniProt Code:Q9UBD6
NCBI GenInfo Identifier:74734928
NCBI Gene ID:51458
NCBI Accession:Q9UBD6.1
UniProt Secondary Accession:Q9UBD6,Q6X3Y4, A8K4D4,
UniProt Related Accession:Q9UBD6
Molecular Weight:479
NCBI Full Name:Ammonium transporter Rh type C
NCBI Synonym Full Names:Rh family, C glycoprotein
NCBI Official Symbol:RHCG  
NCBI Official Synonym Symbols:RHGK; PDRC2; C15orf6; SLC42A3  
NCBI Protein Information:ammonium transporter Rh type C; Rh type C glycoprotein; rh glycoprotein kidney; tumor-related protein DRC2; rh family type C glycoprotein; Rhesus blood group, C glycoprotein; rhesus blood group family type C glycoprotein
UniProt Protein Name:Ammonium transporter Rh type C
UniProt Synonym Protein Names:Rh glycoprotein kidney; Rhesus blood group family type C glycoprotein; Rh family type C glycoprotein; Rh type C glycoprotein; Tumor-related protein DRC2
Protein Family:Ammonium transporter
UniProt Gene Name:RHCG  
UniProt Entry Name:RHCG_HUMAN
Anti-RHCG Antibody (CAB16124)Western blot analysis of extracts of various cell lines, using RHCG antibody (CAB16124) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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