Cell Biology Antibodies 14
Anti-RGS2 Antibody (CAB1795)
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- SKU:
- CAB1795
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Antibody Name: | Anti-RGS2 Antibody (CAB1795) |
| Antibody SKU: | CAB1795 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting, Immunohistochemistry |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human RGS2 (NP_002914.1). |
| Application: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human RGS2 (NP_002914.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MQSA MFLA VQHD CRPM DKSA GSGH KSEE KREK MKRT LLKD WKTR LSYF LQNS STPG KPKT GKKS KQQA FIKP SPEE AQLW SEAF DELL ASKY GLAA FRAF LKSE FCEE NIEF WLAC EDFK KTKS PQKL SSKA RKIY TDFI EKEA PKEI NIDF QTKT LIAQ NIQE ATSG CFTT AQKR VYSL MENN SYPR FLES EFYQ DLCK KPQI TTEP HAT |
| Cellular Location: | Cell membrane, Cytoplasm, Mitochondrion, Nucleus, nucleolus |
| Calculated MW: | 20kDa/22kDa/23kDa/24kDa |
| Observed MW: | Refer to figures |
| Synonyms: | RGS2, G0S8 |
| Background: | Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis. |
 | Immunohistochemistry of paraffin-embedded human colon using RGS2 Rabbit pAb at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with IHC staining protocol. |
 | Immunohistochemistry of paraffin-embedded human esophagus using RGS2 Rabbit pAb at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with IHC staining protocol. |
 | Immunohistochemistry of paraffin-embedded human breast cancer using RGS2 Rabbit pAb at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with IHC staining protocol. |
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