Antibody Name:	Anti-RGS2 Antibody (CAB1795)
Antibody SKU:	CAB1795
Antibody Size:	50µL, 100µL
Application:	Western blotting, Immunohistochemistry
Reactivity:	Human
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human RGS2 (NP_002914.1).

Application:	Western blotting, Immunohistochemistry
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:	Human
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human RGS2 (NP_002914.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MQSA MFLA VQHD CRPM DKSA GSGH KSEE KREK MKRT LLKD WKTR LSYF LQNS STPG KPKT GKKS KQQA FIKP SPEE AQLW SEAF DELL ASKY GLAA FRAF LKSE FCEE NIEF WLAC EDFK KTKS PQKL SSKA RKIY TDFI EKEA PKEI NIDF QTKT LIAQ NIQE ATSG CFTT AQKR VYSL MENN SYPR FLES EFYQ DLCK KPQI TTEP HAT
Cellular Location:	Cell membrane, Cytoplasm, Mitochondrion, Nucleus, nucleolus
Calculated MW:	20kDa/22kDa/23kDa/24kDa
Observed MW:	Refer to figures

Synonyms:

RGS2, G0S8

Background:

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.

	Immunohistochemistry of paraffin-embedded human colon using RGS2 Rabbit pAb at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with IHC staining protocol.
	Immunohistochemistry of paraffin-embedded human esophagus using RGS2 Rabbit pAb at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with IHC staining protocol.
	Immunohistochemistry of paraffin-embedded human breast cancer using RGS2 Rabbit pAb at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with IHC staining protocol.