Cell Biology Antibodies 9
Anti-RGS16 Antibody (CAB4078)
(No reviews yet)
Write a Review
- SKU:
- CAB4078
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RGS16 Antibody |
| Antibody SKU: | CAB4078 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human RGS16 (NP_002919.3). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human RGS16 (NP_002919.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MCRT LAAF PTTC LERA KEFK TRLG IFLH KSEL GCDT GSTG KFEW GSKH SKEN RNFS EDVL GWRE SFDL LLSS KNGV AAFH AFLK TEFS EENL EFWL ACEE FKKI RSAT KLAS RAHQ IFEE FICS EAPK EVNI DHET HELT RMNL QTAT ATCF DAAQ GKTR TLME KDSY PRFL KSPA YRDL AAQA SAAS ATLS SCSL DEPS HT |
| Gene ID: | 6004 |
| Uniprot: | O15492 |
| Cellular Location: | |
| Calculated MW: | 22kDa |
| Observed MW: | 22kDa |
| Synonyms: | RGS16, A28-RGS14, A28-RGS14P, RGS-R |
| Background: | The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. |
| UniProt Protein Function: | RGS1: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q31 Cellular Component: cytoplasm; plasma membrane Molecular Function:calmodulin binding; GTPase activator activity Biological Process: immune response; G-protein signaling, adenylate cyclase inhibiting pathway; signal transduction; positive regulation of GTPase activity |
| NCBI Summary: | This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O15492 |
| NCBI GenInfo Identifier: | 115387108 |
| NCBI Gene ID: | 5996 |
| NCBI Accession: | NP_002913.3 |
| UniProt Secondary Accession: | O15492,O15492, P97428, P56700, |
| UniProt Related Accession: | Q08116 |
| Molecular Weight: | 23,858 Da |
| NCBI Full Name: | regulator of G-protein signaling 1 |
| NCBI Synonym Full Names: | regulator of G-protein signaling 1 |
| NCBI Official Symbol: | RGS1 |
| NCBI Official Synonym Symbols: | 1R20; BL34; IER1; IR20 |
| NCBI Protein Information: | regulator of G-protein signaling 1; early response protein 1R20; B-cell activation protein BL34; regulator of G-protein signalling 1; immediate-early response 1, B-cell specific |
| UniProt Protein Name: | Regulator of G-protein signaling 1 |
| UniProt Synonym Protein Names: | B-cell activation protein BL34; Early response protein 1R20 |
| Protein Family: | Regulator of G-protein signaling |
| UniProt Gene Name: | RGS1 |
| UniProt Entry Name: | RGS1_HUMAN |
 | Western blot analysis of extracts of mouse lung, using RGS16 antibody (CAB4078) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक