Cell Biology Antibodies 13
Anti-RFX2 Antibody (CAB17525)
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- SKU:
- CAB17525
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RFX2 Antibody |
| Antibody SKU: | CAB17525 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 295-450 of human RFX2 (NP_000626.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | DU145 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 295-450 of human RFX2 (NP_000626.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MHQK PRYR PAQK TDSL GDSG SHSG LHST PEQT MAVQ SQHH QQYI DVSH VFPE FPAP DLGS FLLQ DGVT LHDV KALQ LVYR RHCE ATVD VVMN LQFH YIEK LWLS FWNS KASS SDGP TSLP ASDE DPEG AVLP KDKL ISLC QCDP ILRW MRSC DHIL |
| Gene ID: | 5990 |
| Uniprot: | P48378 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 80kDa |
 | Western blot - RFX2 Polyclonal Antibody (CAB17525) |
| Synonyms: | RFX2 |
| Background: | This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | RFX2: a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytoplasm; nucleus Molecular Function:DNA binding; transcription factor activity Biological Process: acrosome formation; cilium biogenesis; regulation of transcription from RNA polymerase II promoter; spermatid development |
| NCBI Summary: | This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P48378 |
| NCBI GenInfo Identifier: | 254763325 |
| NCBI Gene ID: | 5990 |
| NCBI Accession: | P48378.2 |
| UniProt Secondary Accession: | P48378,Q6IQ44, Q8SNA2, A8K581, B3KNC4, |
| UniProt Related Accession: | P48378 |
| Molecular Weight: | 77,268 Da |
| NCBI Full Name: | DNA-binding protein RFX2 |
| NCBI Synonym Full Names: | regulatory factor X2 |
| NCBI Official Symbol: | RFX2 |
| NCBI Protein Information: | DNA-binding protein RFX2 |
| UniProt Protein Name: | DNA-binding protein RFX2 |
| UniProt Synonym Protein Names: | Regulatory factor X 2 |
| Protein Family: | RFX-like DNA-binding protein |
| UniProt Gene Name: | RFX2 |
| UniProt Entry Name: | RFX2_HUMAN |
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