Cell Biology Antibodies 1

Anti-RFTN1 Antibody (CAB10430)

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SKU:
CAB10430
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-RFTN1 Antibody
Antibody SKU:CAB10430
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RFTN1 (NP_055965.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:A-549, Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RFTN1 (NP_055965.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGCG LNKL EKRD EKRP GNIY STLK RPQV ETKI DVSY EYRF LEFT TLSA AELP GSSA VRLA SLRD LPAQ LLEL YQQG FSLA ALHP FVQP THER EKTP LEHI FRAI LIKK TDRS QKTD LHNE GYIL ELDC CSSL DHPT DQKL IPEF IKKI QEAA SQGL KFVG VIPQ YHSS VNSA GSSA PVST ANST EDAR DAKN ARGD HASL ENEK PGTG DVCS APAG RNQS PEPS SGPR GEVP LAKQ PSSP SGEG DGGE LSPQ GVSK TLDG
Gene ID:23180
Uniprot:Q14699
Cellular Location:Cell membrane, Lipid-anchor
Calculated MW:63kDa
Observed MW:70kDa
Synonyms:RFTN1, MIG2, PIB10, PIG9, RAFTLIN, raftlin
Background:
UniProt Protein Function:RFTN1: May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor- mediated signaling. Belongs to the raftlin family.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 3p24.3

Cellular Component: cytoplasm; endosome; lipid raft; plasma membrane; protein complex

Molecular Function:double-stranded RNA binding

Biological Process: B cell receptor signaling pathway; dsRNA transport; growth; interleukin-17 production; lipid raft formation; protein transport into lipid raft; response to exogenous dsRNA; T cell antigen processing and presentation; T cell receptor signaling pathway; toll-like receptor 3 signaling pathway

UniProt Code:Q14699
NCBI GenInfo Identifier:115502444
NCBI Gene ID:23180
NCBI Accession:Q14699.4
UniProt Secondary Accession:Q14699,Q0D2G0, Q496Y2, Q4QQI7, Q5JB48, Q7Z7P2,
UniProt Related Accession:Q14699
Molecular Weight:63,146 Da
NCBI Full Name:Raftlin
NCBI Synonym Full Names:raftlin, lipid raft linker 1
NCBI Official Symbol:RFTN1  
NCBI Official Synonym Symbols:MIG2; PIG9; PIB10; RAFTLIN  
NCBI Protein Information:raftlin
UniProt Protein Name:Raftlin
UniProt Synonym Protein Names:Cell migration-inducing gene 2 protein; Raft-linking protein
Protein Family:Raftlin
UniProt Gene Name:RFTN1  
UniProt Entry Name:RFTN1_HUMAN
Anti-RFTN1 Antibody (CAB10430)Western blot analysis of extracts of various cell lines, using RFTN1 antibody (CAB10430) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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