Antibody Name:	Anti-RETN Antibody
Antibody SKU:	CAB2551
Antibody Size:	20uL, 50uL, 100uL
Application:	IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human RETN (NP_001180303.1).

Application:	IHC
Recommended Dilution:	IHC 1:50 - 1:100
Reactivity:	Human, Mouse, Rat
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human RETN (NP_001180303.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MKAL CLLL LPVL GLLV SSKT LCSM EEAI NERI QEVA GSLI FRAI SSIG LECQ SVTS RGDL ATCP RGFA VTGC TCGS ACGS WDVR AETT CHCQ CAGM DWTG ARCC RVQP
Gene ID:	56729
Uniprot:	Q9HD89
Cellular Location:	Secreted
Calculated MW:	8kDa/11kDa
Observed MW:	Refer to figures

Synonyms:

RETN, ADSF, FIZZ3, RETN1, RSTN, XCP1, resistin

Background:

This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

UniProt Protein Function:	resistin: Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Belongs to the resistin/FIZZ family.
UniProt Protein Details:	Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: extracellular space; nucleus Molecular Function:hormone activity Biological Process: fat cell differentiation; response to mechanical stimulus; positive regulation of smooth muscle cell proliferation; positive regulation of smooth muscle cell migration; positive regulation of synaptic transmission; aging; response to insulin stimulus Disease: Diabetes Mellitus, Noninsulin-dependent
NCBI Summary:	This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
UniProt Code:	Q9HD89
NCBI GenInfo Identifier:	18202962
NCBI Gene ID:	56729
NCBI Accession:	Q9HD89.1
UniProt Secondary Accession:	Q9HD89,Q540D9, Q76B53, D6W649,
UniProt Related Accession:	Q9HD89
Molecular Weight:	8,686 Da
NCBI Full Name:	Resistin
NCBI Synonym Full Names:	resistin
NCBI Official Symbol:	RETN
NCBI Official Synonym Symbols:	ADSF; RSTN; XCP1; FIZZ3; RETN1
NCBI Protein Information:	resistin; resistin delta2; found in inflammatory zone 3; cysteine-rich secreted protein FIZZ3; adipose tissue-specific secretory factor; cysteine-rich secreted protein A12-alpha-like 2; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1
UniProt Protein Name:	Resistin
UniProt Synonym Protein Names:	Adipose tissue-specific secretory factor; ADSF; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2; Cysteine-rich secreted protein FIZZ3
Protein Family:	Resistin
UniProt Gene Name:	RETN
UniProt Entry Name:	RETN_HUMAN

	Immunohistochemistry of paraffin-embedded human stomach using RETN antibody (CAB2551) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded mouse lung using RETN antibody (CAB2551) at dilution of 1:100 (40x lens).