Cell Biology Antibodies 18
Anti-RECQL5 Antibody (CAB18346)
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- SKU:
- CAB18346
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RECQL5 Antibody |
| Antibody SKU: | CAB18346 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human RECQL5 (NP_004250.4). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human RECQL5 (NP_004250.4). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9400 |
| Uniprot: | O94762 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | ESG, BCE1, ESG4, GRG4, BCE-1, Grg-4, E(spI), E(spl), RECQL5, RECQ5 |
| Background: |
| UniProt Protein Function: | Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination. |
| NCBI Summary: | The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] |
| UniProt Code: | O94762 |
| NCBI GenInfo Identifier: | 22654276 |
| NCBI Gene ID: | 9400 |
| NCBI Accession: | O94762.2 |
| UniProt Secondary Accession: | O94762,Q6P4G0, Q9H0B1, Q9P1W7, Q9UNC8, |
| UniProt Related Accession: | O94762 |
| Molecular Weight: | 106,051 Da |
| NCBI Full Name: | ATP-dependent DNA helicase Q5 |
| NCBI Synonym Full Names: | RecQ like helicase 5 |
| NCBI Official Symbol: | RECQL5 |
| NCBI Official Synonym Symbols: | RECQ5 |
| NCBI Protein Information: | ATP-dependent DNA helicase Q5 |
| UniProt Protein Name: | ATP-dependent DNA helicase Q5 |
| UniProt Synonym Protein Names: | DNA helicase, RecQ-like type 5; RecQ5; RecQ protein-like 5 |
| Protein Family: | ATP-dependent DNA helicase |
| UniProt Gene Name: | RECQL5 |
| UniProt Entry Name: | RECQ5_HUMAN |
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