Cell Biology Antibodies 11
Anti-RCN2 Antibody (CAB7721)
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- SKU:
- CAB7721
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RCN2 Antibody |
| Antibody SKU: | CAB7721 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-180 of human RCN2 (NP_002893.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, NCI-H460, U-251MG, MCF7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-180 of human RCN2 (NP_002893.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GKAE ELHY PLGE RRSD YDRE ALLG VQED VDEY VKLG HEEQ QKRL QAII KKID LDSD GFLT ESEL SSWI QMSF KHYA MQEA KQQF VEYD KNSD DTVT WDEY NIQM YDRV IDFD ENTA LDDA EEES FRKL HLKD KKRF EKAN QDSG PGLS LEEF IAFE HP |
| Gene ID: | 5955 |
| Uniprot: | Q14257 |
| Cellular Location: | Endoplasmic reticulum lumen |
| Calculated MW: | 36kDa/39kDa |
| Observed MW: | 40kDa |
| Synonyms: | RCN2, E6BP, ERC-55, ERC55, TCBP49 |
| Background: | The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | RCN2: Not known. Binds calcium. Belongs to the CREC family. |
| UniProt Protein Details: | Protein type:Endoplasmic reticulum Chromosomal Location of Human Ortholog: 15q23 Cellular Component: endoplasmic reticulum lumen; endoplasmic reticulum; nucleolus Molecular Function:protein binding; calcium ion binding |
| NCBI Summary: | The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012] |
| UniProt Code: | Q14257 |
| NCBI GenInfo Identifier: | 2493460 |
| NCBI Gene ID: | 5955 |
| NCBI Accession: | Q14257.1 |
| UniProt Related Accession: | Q14257 |
| Molecular Weight: | |
| NCBI Full Name: | Reticulocalbin-2 |
| NCBI Synonym Full Names: | reticulocalbin 2 |
| NCBI Official Symbol: | RCN2 |
| NCBI Official Synonym Symbols: | E6BP; ERC55; ERC-55; TCBP49 |
| NCBI Protein Information: | reticulocalbin-2 |
| UniProt Protein Name: | Reticulocalbin-2 |
| UniProt Synonym Protein Names: | Calcium-binding protein ERC-55; E6-binding protein; E6BP |
| Protein Family: | Reticulocalbin |
| UniProt Gene Name: | RCN2 |
| UniProt Entry Name: | RCN2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RCN2 antibody (CAB7721) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human stomach using RCN2 antibody (CAB7721) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat heart using RCN2 antibody (CAB7721) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse heart using RCN2 antibody (CAB7721) at dilution of 1:100 (40x lens). |
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OverviewProduct Name:Recombinant Human RCN2 (C-6His)Product Code:RPES6382Size:10µgSpecies:HumanExpression Host:
