Cell Cycle Antibodies 1
Anti-RCC2 Antibody (CAB13105)
(No reviews yet)
Write a Review
- SKU:
- CAB13105
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
| Antibody Name: | Anti-RCC2 Antibody |
| Antibody SKU: | CAB13105 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 323-522 of human RCC2 (NP_001129676.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-87MG, Jurkat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 323-522 of human RCC2 (NP_001129676.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QILP VPNV VVRD VACG ANHT LVLD SQKR VFSW GFGG YGRL GHAE QKDE MVPR LVKL FDFP GRGA SQIY AGYT CSFA VSEV GGLF FWGA TNTS REST MYPK AVQD LCGW RIRS LACG KSSI IVAA DEST ISWG PSPT FGEL GYGD HKPK SSTA AQEV KTLD GIFS EQVA MGYS HSLV IARD ESET EKEK IKKL PEYN PRTL |
| Gene ID: | 55920 |
| Uniprot: | Q9P258 |
| Cellular Location: | Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, nucleolus, spindle |
| Calculated MW: | 56kDa |
| Observed MW: | 55kDa |
| Synonyms: | RCC2, TD-60 |
| Background: | The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomarker for colorectal cancer. |
| UniProt Protein Function: | TD-60: Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1. Binds preferentially to the nucleotide-free form of RAC1. Interacts with microtubules. |
| UniProt Protein Details: | Protein type:Nucleolus; GEFs, misc.; GEFs Chromosomal Location of Human Ortholog: 1p36.13 Cellular Component: cytosol; membrane; midbody Molecular Function:microtubule binding; protein binding; protein domain specific binding; protein kinase binding; Rac GTPase binding; small GTPase binding Biological Process: focal adhesion formation; integrin-mediated signaling pathway; negative regulation of focal adhesion formation; positive regulation of attachment of spindle microtubules to kinetochore; regulation of cell migration; sister chromatid cohesion |
| UniProt Code: | Q9P258 |
| NCBI GenInfo Identifier: | 71152033 |
| NCBI Gene ID: | 55920 |
| NCBI Accession: | Q9P258.2 |
| UniProt Secondary Accession: | Q9P258,Q8IVL9, Q9BSN6, Q9NPV8, |
| UniProt Related Accession: | Q9P258 |
| Molecular Weight: | 56,085 Da |
| NCBI Full Name: | Protein RCC2 |
| NCBI Synonym Full Names: | regulator of chromosome condensation 2 |
| NCBI Official Symbol: | RCC2 |
| NCBI Official Synonym Symbols: | TD-60 |
| NCBI Protein Information: | protein RCC2 |
| UniProt Protein Name: | Protein RCC2 |
| UniProt Synonym Protein Names: | RCC1-like protein TD-60; Telophase disk protein of 60 kDa |
| Protein Family: | Protein |
| UniProt Gene Name: | RCC2 |
| UniProt Entry Name: | RCC2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RCC2 antibody (CAB13105) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
View AllClose
Related Products
Anti-XPD/ERCC2 Antibody (CAB19241)
OverviewProduct Name:XPD/ERCC2 Rabbit mAbProduct Code:CAB19241Size:20uL, 50uL, 100uLSynonyms:ERCC2, COFS2, EM9, TFIIH, TTD, TTD1, XPD, E
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक