Name: Anti-RCBTB2 Antibody (CAB3785)
Brand: Signal Transduction Antibodies 2
SKU: CAB3785
Availability: OutOfStock

Antibody Name:	Anti-RCBTB2 Antibody
Antibody SKU:	CAB3785
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 362-551 of human RCBTB2 (NP_001259.1).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	U-87MG, MCF7, Jurkat, K-562, Mouse pancreas, Rat thymus

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 362-551 of human RCBTB2 (NP_001259.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	TPAV TWRL LSVE PDDH LTVA ESLK REFD NPDT ADLK FLVD GKYI YAHK VLLK IRCE HFRS SLED NEDD IVEM SEFS YPVY RAFL EYLY TDSI SLSP EEAV GLLD LATF YREN RLKK LCQQ TIKQ GICE ENAI ALLS AAVK YDAQ DLEE FCFR FCIN HLTV VTQT SGFA EMDH DLLK NFIS KASR VGAF KN
Gene ID:	1102
Uniprot:	O95199
Cellular Location:
Calculated MW:	57kDa/60kDa
Observed MW:	60kDa

Synonyms:	RCBTB2, CHC1L, RLG
Background:	This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants.

UniProt Protein Function:	RCBTB2: 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Chromosomal Location of Human Ortholog: 13q14.3 Molecular Function:protein binding; Ran guanyl-nucleotide exchange factor activity
NCBI Summary:	This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
UniProt Code:	O95199
NCBI GenInfo Identifier:	74739686
NCBI Gene ID:	1102
NCBI Accession:	O95199.1
UniProt Secondary Accession:	O95199,B2RDW8,
UniProt Related Accession:	O95199
Molecular Weight:	57,769 Da
NCBI Full Name:	RCC1 and BTB domain-containing protein 2
NCBI Synonym Full Names:	RCC1 and BTB domain containing protein 2
NCBI Official Symbol:	RCBTB2
NCBI Official Synonym Symbols:	RLG; CHC1L
NCBI Protein Information:	RCC1 and BTB domain-containing protein 2
UniProt Protein Name:	RCC1 and BTB domain-containing protein 2
UniProt Synonym Protein Names:	Chromosome condensation 1-like; CHC1-L; RCC1-like G exchanging factor; Regulator of chromosome condensation and BTB domain-containing protein 2
Protein Family:	RCC1 and BTB domain-containing protein
UniProt Gene Name:	RCBTB2
UniProt Entry Name:	RCBT2_HUMAN

Western blot analysis of extracts of various cell lines, using RCBTB2 antibody (CAB3785) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.

Antibodies

RCBTB2 Antibody (PACO11779)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)