Cell Cycle Antibodies 1
Anti-RCBTB1 Antibody (CAB16542)
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- SKU:
- CAB16542
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
| Antibody Name: | Anti-RCBTB1 Antibody |
| Antibody SKU: | CAB16542 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RCBTB1 (NP_060661.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RCBTB1 (NP_060661.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MVDV GKWP IFTL LSPQ EIAS IRKA CVFG TSAS EALY VTDN DEVF VFGL NYSN CLGT GDNQ STLV PKKL EGLC GKKI KSLS YGSG PHVL LSTE DGVV YAWG HNGY SQLG NGTT NQGI APVQ |
| Gene ID: | 55213 |
| Uniprot: | Q8NDN9 |
| Cellular Location: | Nucleus |
| Calculated MW: | 37kDa/58kDa |
| Observed MW: | Refer to figures |
| Synonyms: | RCBTB1, CLLD7, CLLL7, GLP, RDEOA |
| Background: | This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. |
| UniProt Protein Function: | RCBTB1: May be involved in cell cycle regulation by chromatin remodeling. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Transcription regulation Chromosomal Location of Human Ortholog: 13q14 Cellular Component: cytoplasm Disease: Alcohol Dependence |
| NCBI Summary: | This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8NDN9 |
| NCBI GenInfo Identifier: | 74751227 |
| NCBI Gene ID: | 55213 |
| NCBI Accession: | Q8NDN9.1 |
| UniProt Secondary Accession: | Q8NDN9,Q8IY29, Q969U9, |
| UniProt Related Accession: | Q8NDN9 |
| Molecular Weight: | 37,591 Da |
| NCBI Full Name: | RCC1 and BTB domain-containing protein 1 |
| NCBI Synonym Full Names: | RCC1 and BTB domain containing protein 1 |
| NCBI Official Symbol: | RCBTB1 |
| NCBI Official Synonym Symbols: | GLP; CLLD7; CLLL7 |
| NCBI Protein Information: | RCC1 and BTB domain-containing protein 1 |
| UniProt Protein Name: | RCC1 and BTB domain-containing protein 1 |
| UniProt Synonym Protein Names: | Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; Regulator of chromosome condensation and BTB domain-containing protein 1 |
| Protein Family: | RCC1 and BTB domain-containing protein |
| UniProt Gene Name: | RCBTB1 |
| UniProt Entry Name: | RCBT1_HUMAN |
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