Epigenetics & Nuclear Signaling Antibodies 3

Anti-RBMY1F Antibody (CAB16604)

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SKU:
CAB16604
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-RBMY1F Antibody
Antibody SKU:CAB16604
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human RBMY1F (NP_689798.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:Rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human RBMY1F (NP_689798.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MVEA DHPG KLFI GGLN RETN EKML KAVF GKHG PISE VLLI KDRT SKSR GFAF ITFE NPAD AKNA AKDM NGTS LHGK AIKV
Gene ID:159163
Uniprot:Q15415
Cellular Location:Nucleus
Calculated MW:47kDa/55kDa
Observed MW:56kDa
Synonyms:RBMY1F, YRRM2, RNA binding motif protein, Y-linked, family 1, member F
Background:This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked.
UniProt Protein Function:RBMY1F: RNA-binding protein which may be involved in spermatogenesis. Required for sperm development, possibly by participating in pre-mRNA splicing in the testis. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: Yq11.223

Molecular Function:identical protein binding; protein binding

NCBI Summary:This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. This protein likely functions as a splicing factor during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes, though several likely encode functional proteins. [provided by RefSeq, Mar 2016]
UniProt Code:Q15415
NCBI GenInfo Identifier:56090529
NCBI Gene ID:378951
NCBI Accession:NP_001006117.2
UniProt Secondary Accession:Q15415,B2R916,
UniProt Related Accession:Q15415
Molecular Weight:71.69kD
NCBI Full Name:RNA-binding motif protein, Y chromosome, family 1 member F/J
NCBI Synonym Full Names:RNA binding motif protein, Y-linked, family 1, member J
NCBI Official Symbol:RBMY1J  
NCBI Protein Information:RNA-binding motif protein, Y chromosome, family 1 member F/J
UniProt Protein Name:RNA-binding motif protein, Y chromosome, family 1 member F/J
UniProt Synonym Protein Names:Y chromosome RNA recognition motif 2
Protein Family:RNA-binding motif protein
UniProt Gene Name:RBMY1F  
Anti-RBMY1F Antibody (CAB16604)Western blot analysis of extracts of rat kidney, using RBMY1F antibody (CAB16604) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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