Cell Biology Antibodies 18
Anti-RBMY1A1 Antibody (CAB18376)
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- SKU:
- CAB18376
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RBMY1A1 Antibody |
| Antibody SKU: | CAB18376 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human RBMY1A1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human RBMY1A1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5940 |
| Uniprot: | P0DJD3 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | RBM, RBM1, RBM2, RBMY, RBMY1C, YRRM1, YRRM2, RBMY1A1 |
| Background: |
| UniProt Protein Function: | RBMY1A1: RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs. Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3. |
| UniProt Protein Details: | Protein type:RNA splicing Chromosomal Location of Human Ortholog: Yq11.223 Molecular Function:mRNA binding; protein binding Biological Process: regulation of alternative nuclear mRNA splicing, via spliceosome Disease: Spermatogenic Failure, Y-linked, 2 |
| NCBI Summary: | This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. This protein is thought to function as a splicing regulator during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes, though several likely encode functional proteins. [provided by RefSeq, Mar 2016] |
| UniProt Code: | P0DJD3 |
| NCBI GenInfo Identifier: | 1004170692 |
| NCBI Gene ID: | 5940 |
| NCBI Accession: | NP_001307873.1 |
| UniProt Secondary Accession: | P0DJD3,Q15376, Q15377, Q15414, Q6NSB5, Q86VU6, Q8NHR0 |
| UniProt Related Accession: | P0DJD3 |
| Molecular Weight: | 55.4kD |
| NCBI Full Name: | RNA-binding motif protein, Y chromosome, family 1 member A1 isoform 2 |
| NCBI Synonym Full Names: | RNA binding motif protein, Y-linked, family 1, member A1 |
| NCBI Official Symbol: | RBMY1A1 |
| NCBI Official Synonym Symbols: | RBM; RBM1; RBM2; RBMY; YRRM1; YRRM2; RBMY1C |
| NCBI Protein Information: | RNA-binding motif protein, Y chromosome, family 1 member A1 |
| UniProt Protein Name: | RNA-binding motif protein, Y chromosome, family 1 member A1 |
| UniProt Synonym Protein Names: | RNA-binding motif protein 1; RNA-binding motif protein 2; Y chromosome RNA recognition motif 1; hRBMY |
| Protein Family: | RNA-binding motif protein |
| UniProt Gene Name: | RBMY1A1 |
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