Immunology Antibodies 3

Anti-RBM15B Antibody (CAB9873)

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SKU:
CAB9873
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology

Description

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Antibody Name:Anti-RBM15B Antibody
Antibody SKU:CAB9873
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 540-720 of human RBM15B (NP_037418.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HT-29, SH-SY5Y, HepG2, BT-474, Mouse pancreas, Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 540-720 of human RBM15B (NP_037418.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DRDR TFLE GDWT SPSK SSDR RNSL EGYS RSVR SRSG ERWG ADGD RGLP KPWE ERRK RRSL SSDR GRTT HSPY EERS RTKG SGQQ SERG SDRT PERS RKEN HSSE GTKE SSSN SLSN SRHG AEER GHHH HHHE AADS SHGK KARD SERN HRTT EAEP KPLE EPKH ETKK LKNL SEYA QTLQ L
Gene ID:29890
Uniprot:Q8NDT2
Cellular Location:Nucleus, nucleoplasm
Calculated MW:63kDa/97kDa
Observed MW:97kDa/107kDa
Synonyms:RBM15B, HUMAGCGB, OTT3
Background:
UniProt Protein Function:RBM15B: May function in the regulation of alternative or illicit splicing. Belongs to the RRM Spen family.
UniProt Protein Details:

Protein type:RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 3p21.2

Cellular Component: nucleolus; nucleoplasm

Molecular Function:nucleic acid binding; protein binding; RNA binding

Biological Process: negative regulation of transcription, DNA-dependent; nucleocytoplasmic transport; regulation of alternative nuclear mRNA splicing, via spliceosome

NCBI Summary:Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]
UniProt Code:Q8NDT2
NCBI GenInfo Identifier:229463030
NCBI Gene ID:29890
NCBI Accession:Q8NDT2.3
UniProt Secondary Accession:Q8NDT2,Q6QE19, Q9BV96, A4QPG7,
UniProt Related Accession:Q8NDT2
Molecular Weight:97kDa
NCBI Full Name:Putative RNA-binding protein 15B
NCBI Synonym Full Names:RNA binding motif protein 15B
NCBI Official Symbol:RBM15B  
NCBI Official Synonym Symbols:OTT3; HUMAGCGB  
NCBI Protein Information:putative RNA-binding protein 15B
UniProt Protein Name:Putative RNA-binding protein 15B
UniProt Synonym Protein Names:One-twenty two protein 3; HuOTT3; RNA-binding motif protein 15B
Protein Family:Putative RNA-binding protein
UniProt Gene Name:RBM15B  
Anti-RBM15B Polyclonal Antibody (CAB9873)Western blot analysis of extracts of various cell lines, using RBM15B Antibody (CAB9873) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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