Epigenetics & Nuclear Signaling Antibodies 3

Anti-RBM10 Antibody (CAB4209)

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SKU:
CAB4209
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-RBM10 Antibody
Antibody SKU:CAB4209
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human RBM10 (NP_005667.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:Jurkat, MCF7, LO2, 293T
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human RBM10 (NP_005667.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEYE RRGG RGDR TGRY GATD RSQD DGGE NRSR DHDY RDMD YRSY PREY GSQE GKHD YDDS SEEQ SAED SYEA SPGS ETQR RRRR RHRH SPTG PPGF PRDG DYRD QDYR TEQG EEEE EEED EEEE EKAS NIVM LRML PQAA TEDD IRGQ LQSH GVQA REVR LMRN KSSG QSRG FAFV EFSH
Gene ID:8241
Uniprot:P98175
Cellular Location:Nucleus
Calculated MW:94kDa/103kDa
Observed MW:105kDa
Synonyms:RBM10, DXS8237E, GPATC9, GPATCH9, S1-1, TARPS, ZRANB5
Background:This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants.
UniProt Protein Function:May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A).
NCBI Summary:This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011]
UniProt Code:P98175
NCBI GenInfo Identifier:218512116
NCBI Gene ID:8241
NCBI Accession:P98175.3
UniProt Secondary Accession:P98175,Q14136, Q5JRR2, Q9BTE4, Q9BTX0, Q9NTB1, C4AM81
UniProt Related Accession:P98175
Molecular Weight:930
NCBI Full Name:RNA-binding protein 10
NCBI Synonym Full Names:RNA binding motif protein 10
NCBI Official Symbol:RBM10  
NCBI Official Synonym Symbols:S1-1; TARPS; GPATC9; ZRANB5; GPATCH9; DXS8237E  
NCBI Protein Information:RNA-binding protein 10; RNA-binding protein S1-1; g patch domain-containing protein 9
UniProt Protein Name:RNA-binding protein 10
UniProt Synonym Protein Names:G patch domain-containing protein 9; RNA-binding motif protein 10; RNA-binding protein S1-1; S1-1
Protein Family:RNA-binding protein
UniProt Gene Name:RBM10  
UniProt Entry Name:RBM10_HUMAN
Anti-RBM10 Antibody (CAB4209)Western blot analysis of extracts of various cell lines, using RBM10 antibody (CAB4209) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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