Anti-RBCK1 Antibody (CAB20468)
- SKU:
- CAB20468
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- XAP3
- Synonyms:
- XAP4
- Synonyms:
- HOIL1
- Synonyms:
- PBMEI
- Synonyms:
- PGBM1
- Synonyms:
- RBCK2
- Synonyms:
- RNF54
- Synonyms:
- HOIL-1
- Synonyms:
- ZRANB4
- Synonyms:
- C20orf18
- Synonyms:
- UBCE7IP3
Description
| Product Name: | RBCK1 Rabbit pAb |
| Product Code: | CAB20468 |
| Size: | 50uL, 100uL |
| Synonyms: | XAP3, XAP4, HOIL1, PBMEI, PGBM1, RBCK2, RNF54, HOIL-1, ZRANB4, C20orf18, UBCE7IP3 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human RBCK1. |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, Mouse lung, Rat lung |
| Immunogen: | Recombinant protein of human RBCK1. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10616 |
| Uniprot: | Q9BYM8 |
| Calculated MW: | 57kDa |
| Observed MW: | 58kDa |
| UniProt Protein Function: | RBCK1: a E3 ubiquitin-protein ligase that contains a zf-RanBP (Zn-finger in Ran binding protein) and a zf-C3HC4 (RING finger) domain. Phosphorylation apparently reduces its E3 activity. Functions as a transcriptional activator. Its nuclear translocation is prevented by binding to a splice-variant of RBCK1 that lacks the RING finger domain. Interacts with PKCB1, PKCZ, and accepts ubiquitin from E2 ubiquitin-conjugating enzymes including UBE2L3. Interacts with PKCH. Interacts with the HBV pX/HBx protein, which is required to activate transcription of the viral genome. Three splice-variant isoforms of the human protein have been reported. Protein type: EC 6.3.2.-; Ligase; Ubiquitin conjugating system; Ubiquitin ligase Chromosomal Location of Human Ortholog: 20p13 Cellular Component: cytosol Molecular Function: protein binding; ubiquitin binding; ubiquitin-protein ligase activity Biological Process: activation of NF-kappaB transcription factor; I-kappaB kinase/NF-kappaB cascade; inhibition of NF-kappaB transcription factor; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; T cell receptor signaling pathway Disease: Polyglucosan Body Myopathy, Early-onset, With Or Without Immunodeficiency |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is similar to mouse UIP28/UbcM4 interacting protein. Alternative splicing has been observed at this locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BYM8 |
| NCBI GenInfo Identifier: | 166214993 |
| NCBI Gene ID: | 10616 |
| NCBI Accession: | Q9BYM8.2 |
| UniProt Secondary Accession: | Q9BYM8,O95623, Q86SL2, Q96BS3, Q9BYM9 |
| UniProt Related Accession: | Q9BYM8 |
| Molecular Weight: | 25,654 Da |
| NCBI Full Name: | RanBP-type and C3HC4-type zinc finger-containing protein 1 |
| NCBI Synonym Full Names: | RANBP2-type and C3HC4-type zinc finger containing 1 |
| NCBI Official Symbol: | RBCK1 |
| NCBI Official Synonym Symbols: | XAP3; XAP4; HOIL1; PBMEI; PGBM1; RBCK2; RNF54; HOIL-1; ZRANB4; C20orf18; UBCE7IP3 |
| NCBI Protein Information: | ranBP-type and C3HC4-type zinc finger-containing protein 1 |
| UniProt Protein Name: | RanBP-type and C3HC4-type zinc finger-containing protein 1 |
| UniProt Synonym Protein Names: | HBV-associated factor 4; Heme-oxidized IRP2 ubiquitin ligase 1; HOIL-1; Hepatitis B virus X-associated protein 4; RING finger protein 54; RING-type E3 ubiquitin transferase HOIL-1Curated; Ubiquitin-conjugating enzyme 7-interacting protein 3 |
| Protein Family: | |
| UniProt Gene Name: | RBCK1 |
| UniProt Entry Name: |
Related Products
Anti-RANBP3 Antibody (CAB0092)
OverviewProduct Name:RANBP3 Rabbit mAbProduct Code:CAB0092Size:20uL, 50uL, 100uLSynonyms:RANBP3, ran-binding protein 3
Anti-QK1 Antibody (CAB0193)
OverviewProduct Name:QK1 Rabbit mAbProduct Code:CAB0193Size:20uL, 50uL, 100uLSynonyms:QKI, Hqk, QK, QK1, QK3, hqkI, protein quaking
Anti-DEK Antibody (CAB0315)
OverviewProduct Name:DEK Rabbit mAbProduct Code:CAB0315Size:20uL, 50uL, 100uLSynonyms:D6S231EApplications:WB,
Anti-EXOSC7 Antibody (CAB0501)
OverviewProduct Name:EXOSC7 Rabbit mAbProduct Code:CAB0501Size:20uL, 50uL, 100uLSynonyms:EXOSC7, EAP1, RRP42, Rrp42p, hRrp42p, p8, exoso
Anti-Olig3 Antibody (CAB0600)
OverviewProduct Name:Olig3 Rabbit mAbProduct Code:CAB0600Size:20uL, 50uL, 100uLSynonyms:OLIG3, Bhlhb7, bHLHe20, oligodendrocyte transcri