Cell Biology Antibodies 3

Anti-RAVER1 Antibody (CAB13138)

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SKU:
CAB13138
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-RAVER1 Antibody
Antibody SKU:CAB13138
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 390-490 of human RAVER1 (NP_597709.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:293T, HeLa
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 390-490 of human RAVER1 (NP_597709.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GPAL STAL LQLA LQTQ GQKK PGIL GDSP LGAL QPGA QPAN PLLG ELPA GGGL PPEL PPRR GKPP PLLP SVLG PAGG DREA LGLG PPAA QLTP PPAP VGLR G
Gene ID:125950
Uniprot:Q8IY67
Cellular Location:Cytoplasm, Nucleus
Calculated MW:8kDa/63kDa/77kDa
Observed MW:64kDa
Synonyms:RAVER1
Background:
UniProt Protein Function:RAVER1: Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:RNA-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: nucleus

Molecular Function:nucleic acid binding

Biological Process: nuclear mRNA splicing, via spliceosome

UniProt Code:Q8IY67
NCBI GenInfo Identifier:74759693
NCBI Gene ID:125950
NCBI Accession:Q8IY67.1
UniProt Secondary Accession:Q8IY67,Q8IY60, Q8TF24, A6NMU4,
UniProt Related Accession:Q8IY67
Molecular Weight:8,419 Da
NCBI Full Name:Ribonucleoprotein PTB-binding 1
NCBI Synonym Full Names:ribonucleoprotein, PTB binding 1
NCBI Official Symbol:RAVER1  
NCBI Protein Information:ribonucleoprotein PTB-binding 1
UniProt Protein Name:Ribonucleoprotein PTB-binding 1
UniProt Synonym Protein Names:Protein raver-1
Protein Family:Ribonucleoprotein PTB-binding
UniProt Gene Name:RAVER1  
UniProt Entry Name:RAVR1_HUMAN
Anti-RAVER1 Antibody (CAB13138)Western blot analysis of extracts of various cell lines, using RAVER1 antibody (CAB13138) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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