Anti-RanBP9 Antibody (CAB19238)

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SKU:
CAB19238
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
RANBP9
Synonyms:
BPM-L
Synonyms:
BPM90
Synonyms:
RANBPM
Synonyms:
RanBP7
Synonyms:
ran-binding protein 9
Research Area:
Cell Biology

Description

Product Name:RanBP9 Rabbit mAb
Product Code:CAB19238
Size:20uL, 50uL, 100uL
Synonyms:RANBP9, BPM-L, BPM90, RANBPM, RanBP7, ran-binding protein 9
Applications:WB, IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human RanBP9 .
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:C2C12, RD, C6, Mouse testis, Rat testis
Immunogen:Recombinant protein of human RanBP9 .
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:10048
Uniprot:Q96S59
Cellular Location:Cytoplasm, Nucleus, cytosol
Calculated MW:91kDa
Observed MW:80KDa/91KDa
UniProt Protein Function:RANBP9: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA. Belongs to the RANBP9/10 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Nuclear receptor co-regulator; Adaptor/scaffold; GAPs; GAPs, Ras

Chromosomal Location of Human Ortholog: 6p23

Cellular Component: microtubule associated complex; nucleus; cytosol

Molecular Function:protein binding; enzyme binding; Ran GTPase binding

Biological Process: axon guidance; protein complex assembly; microtubule nucleation

NCBI Summary:This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]
UniProt Code:Q96S59
NCBI GenInfo Identifier:61215334
NCBI Gene ID:10048
NCBI Accession:Q96S59.1
UniProt Related Accession:Q96S59
Molecular Weight:42kDa
NCBI Full Name:Ran-binding protein 9
NCBI Synonym Full Names:RAN binding protein 9
NCBI Official Symbol:RANBP9  
NCBI Official Synonym Symbols:BPM-L; BPM90; RANBPM; RanBP7  
NCBI Protein Information:ran-binding protein 9
UniProt Protein Name:Ran-binding protein 9
UniProt Synonym Protein Names:BPM-L; BPM90; Ran-binding protein M; RanBPM; RanBP7
Protein Family:Ran-binding protein
UniProt Gene Name:RANBP9  
UniProt Entry Name:RANB9_HUMAN
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